clinical: anemic patient

Question 1

What are lab findings for hypoproliferative anemia

Answer 1

Anemias associated with normocytic and normochromic red cells and an inappropriately low reticulocyte response

this includes early iron deficiency anemia

Question 2

Syndrome associated with iron deficiency anemia

Answer 2

Plummer-Vinson Syndrome

Koilonychia
Cheloisis

Question 3

TIBC is _____ in irone deficiency anemia whereas it is usually ______ in anemia of chronic disease

Answer 3

TIBC is high in iron def anemia whereas it is usually low in anemia of chronic disease (check this)

Question 4

Vitamin associated w/ Sideroblastic Anemia

Answer 4

Vitamin B6, cofactor for ALAS needed in heme synthesis

Question 5

Anemia of chronic disease presents as microcytic or normocytic and can lead to iron deficiency, however the lab values differ from iron deficiency in that the TIBC is _______ because _________ and the ferritin is ______

Answer 5

TIBC is low because the acute phase reactants are preventing liver from creating proteins

Question 6

Most common cause of Macrocytic anemia

Answer 6

alcoholism and liver disease

Question 7

Megaloblastic and macrocytic deficiencies of

Answer 7

B12 and folate

Question 8

Old person, memory disturbances, tripped going down the stairs, decreased vibration and position sense (posterior tracts)

Slightly elevated indirect bilirubin from ineffective erythropoesis

Answer 8

Vitamin B12 deficiency

Question 9

Abnormal erythropoeisis, ringed siderblasts, macrocytic anemia, general clonal stem cell disorder that is preleukemia

Answer 9

Myelodysplastic syndrome

Question 10

Increased LDH from RBC membrane rupture, increase indirect bili, reticulocytosis, polychromatosis, low haptoglobin, hemoglobinuria, IgG warm agglutination

Answer 10

Spherocytosis

Question 11

common findings in neutrophils w/ B12 deficiency?

Answer 11

Hypersegmented neuts

Question 12

Dapsone/oxidant damage related hemolysis can be from

Answer 12

G6PD prophylaxis