Clinic-Intestinal Tumors Flashcards
malignant intestinal tumors cause?
colicky pain, obstruction, GI bleeding, weight loss, palpable mass, perforation
3 most common benign tumors of small intestine
adenoma, leiomyoma, lipoma
5 malignant small bowel tumors
adenocarcinoma, carcinoid, lymphoma, leiomyosarcoma, GIST
this rare, neuroendocrine tumor is usually asymptomatic and found in the ileum
carcinoid
carcinoid syndrome sx include?. And more frequently present with carcinoid tumors located in the _____
flushing, wheezing, dyspnea, sweating, diarrhea, hypoTN, RHF; midgut
carcinoid syndrome is associated with ____ -producing malignant tumors arising from ____ cells
serotonin; enteroendocrine
most common benign tumor of distal colon and rectum
hyperplastic polyps
genetic abnormalities in the long arm of chromosome ___ cause juvenile polyposis syndrome
10
most juvenile polyps are felt to be
hamartomas
when _____ are associated with ______, then it is peutz-jeghers syndrome
hamartomas; mucocutaneous hyperpigmentation
P-J syndrome is inherited _____; gene on short arm of chromosome ___
AD; 19
lifetime risk of colon cancer is ____; chance of dying from it is ___
5-6%, 2-3%
colorectal cancer is more common in?
men; ppl over 50
risk factors for CRC
age over 50, colon adenoma, family hx, FAP, cigarettes, grilling red meat
most CRC arises from?
adenomas
