Class#6 - Street drugs Flashcards
Abortion Pill content? use?
- Anti-Progesterone (Mifepristone = RU-486), blocks action of progesterone. Lots of SE.
- Can be used several months after implantation
- Misoprostol given after to regulate hormones to normal levels
Morning after pill content? use?
- High dose of progesterone called plan B
2. Up to 72hours after sex
Shakespeare used?
Cocaine
Get high on cow pasture?
Methane released
Anticholinergic plant drugs?
Belladona = jimson weed, Atropine
Main active component of marijuana? # of cannabinoids? # of other compounds?
THC, 65, 483
Hemp?
Used for fabric, less then 0.3 THC
Cannabis Qc leading?
Cash crop
Alex dumas drug?
Hash
Origin of mari real bad?
New orleans 30s, police scare tactics
Endogenous molecule close to THC?
Anandamide
Mari medicinal uses?
appetite, nausea, anticonvulsivant, glaucoma (not anymore), depression,pain, anxiety
Synthetic THC first? second?
Marinol, Sativex
Cannabis cures cancer?
In vitro true, not in vivo
Synthetic cana.
K2, spice, super dangerous
Strichnine?
stimulant, rat poison also used to wake people up
french tonic with cocaine?
Vin Mariani
Coca-Cola cocaine ever?
No big amount
BAsketball player died of one use of cacaine?
Len Bias
Addiction definition?
Tolerance, withdrawal Sx
Freebase cacaine =
Crack, smoke-able
Amphetamine history?
WWII, then asthma Dx.
How to make meth?
- Pseudoephedrine (IN Sudaphed)
2. Phenylacetic acid (requires ammonia)
Herbal Extacy
Ephedrine
Opiates?
Exsudate from bulb of poppy
Acetyl Morphine=
Heroin
Oxicodone date?
1917
Fentanyl date? x more potent then morphine?
1960, 1000xtimes
Alpha-methyl fentanyl?
1976 china white, 25deaths
Carfentanyl more potent then morphine??
10 000
opioids antagonist?
Naloxone
Peyote Cactus active ingredient? Similar to what NT?
Mescaline, similar to dopamine.
Serotonin Psychedelics?
Psilocybin (mush), Buotenine (Cane toad), LSD
LSD origin?
Lisurgig acid, from Ergot Fungus
Who found LSD? Made it famous?
- Albert Hoffman. 2. Timothy LEary
PCP?
Phencyclidine
Designer drugs?
Properties of known narcotics/illegal drugs but not yet illegal.
1939 - Otto Eisleb - Drug?
Demerol
1947 - Albert Ziering alterted demerol to?
MPPP
1976 - Barry Kidston did?
Tryed making MPPP but went into catatonic state because of MPTP as byproduct. Also in 1982 - new heroin
Why MTPT bad?
MAO makes it into MPP+, Detroys Substancia Nigria, causing Parkinson Disease