Class #5 - Hormones

Question 1

Multiple endocrine neoplasia Sx

Answer 1

Excessive growth
Visual prob. (pituitary)
Low blood sugar (pancreas)
Soft skull (Paratyoid)

Question 2

Discovery of 1st hormone? By who and name?

Answer 2

Ernest Starling

Secretin

Question 3

Hormones def?

Answer 3

Substance release by endocrine glands, chemical messenger that circulate in blood stream, to communicate with another part of the body

Question 4

Secretin release?

Answer 4

Secretin release with rise of HCL in duodenum, signals pancreatice juices

Question 5

Pituitary gland?

Answer 5

Master endocrine gland. Secrete 1ug per day of hormones.

Question 6

PItuitary secretions?

Answer 6

Prolactin ->breast:milk
Somatotropin = GH
ACTH (adenocorticotropic hormone) -> Adrenals
FSH (Follicule stimulating hormone) -> Gonads
TSH (Thyroid stimulating hormone) -> Thyroid

Question 7

Somatotropin?

Answer 7

Produce less with age. Rejuvenating effect yes, but neg. SE: High BP, increase plasma glucose, breast enlargement, carpal tunnel syndrome.)

Question 8

hGH secretagogues?

Answer 8

Just mixture of AA

Question 9

Bovine/porcine somatotropin?

Answer 9

Increase cow milk production/increase musc. mass of porc. But not used b/c people worried.

Question 10

Thyroid gland?

Answer 10

Control metabolism

Question 11

Hypothyroidism Sx? Causes?

Answer 11

Sluggishness, slow heart rate, cold skin, obesity.

Iodine deficiency, auto-immune (Hashimoto’s disease)

Question 12

Hyperthyroidism Sx? Causes?

Answer 12

Anxiety, nervousness, rapid pulse, fatigue, rapid weight loss, protuding eyes.
Tumor, excess, iodine, auto-immune:Graves diseases

Question 13

Treat. of hyperthyroidism?

Answer 13

Methimazole: block iodine formation. Radioactive iodine

Question 14

Parathyroid number, release? Regulate?

Answer 14

4 glands, parathyroid hormone (PTH), calcium and phosphorus metabolism.

Question 15

Calcitonin?

Answer 15

Released by thyroid put CA+ in bones

Question 16

PTH?

Answer 16

Release of bone Ca+ into plasma.

Question 17

Kidney role in Ca+ regulation?

Answer 17

Excrete when too much, kidney stone = too much Ca+ in kidneys.

Question 18

Adrenals stimulated by? Medulla? Cortex?

Answer 18

ACTH
Cathecholamines
Corticostreroids: corstisol, aldosterone, androgens

Question 19

Pancreas? Discovered usefull insuline?

Answer 19

Beta-cells = insuline

Banting, Best and MacLeod

Question 20

Metformin?

Answer 20

Decrease gluc. prod by liver and increse insuline sensitivity

Question 21

Chemical castration?

Answer 21

Androgens blockers: Androcur=cyproterone acetate

Question 22

Finasteride?

Answer 22

Treat. BPH. Prevent conversion of testosterone into dihydrosterone which cause enlarge prostate.

Question 23

Progesterone?

Answer 23

Uterus suitable for implantation of zygote. The pill increse progesterone, reduce pituitary production of TSH