Class 6: Blood and Heart Flashcards
Cardiovascular system refers only to the
heart and blood vessels
Functions of the circulatory system
transport, protect, regulate
adults have…. of blood
4-6 L
blood is a liquid…
connective tissue consisting of cells and extracellular matrix
erthrocytes are
red blood cells
platelets are located…
in bone marrow
leukocytes are
white blood cells
two types of leukocytes
granulocytes, agranulocytes
what machine separates the components of blood?
hematocrit
plasma is the …. portion of blood
liquid
serum is identical to…. except for the absence of …
plasma, fibrinogen
3 major categories of plasma proteins are
albumins, globulins, and fibinogen
plasma proteins are formed by the
liver
viscosity refers to the
resistance of a fluid to flow
osmolarity of blood refers to
the total molarity of those dissolved particles that cannot pass through the blood vessel wall
Hemopoietic tissues produce
blood cells
what tissue produces all seven formed elements?
red bone marrow
Red blood cells are shaped
like a disc with a thick rim
RBCs major function is
gas transport
33% of cytoplasm is…
hemoglobin
Hemoglobin binds…. to …. at it’s center
O2 to ferrous ion (FE2+)
RBC count and Hemoglobin concentration indicate…
the amount of O2 that blood can carry
erythropoiesis (RBC production) needs which nutrients?
Iron, Vitamin B12, Vitamin C and Copper
kidney produces…., which stimulates….
erythropoletin, bone marrow
stimuli for increasing erythropoiesis include
low levels of O2, high altitude, increase in exercise, loss of lung tissue in emphysema
spleen is where red blood cells go to…
die
macrophages are specialized to
digest membrane bits and eat them up
liver removes the…. and secretes it into…
billirubin, bile
polycythemia is an…
excess of RBCs
Dangers of polycythemia are:
increased blood volume, pressure, and viscosity
Anemia is caused by
- inadequate erythropoiesis or hemoglobin synthesis
- hemorrhagic anemia from bleeding
- hemolytic anemia from RBC desctruction
Inadequate B12 can cause
pernicious anemia
3 potential consequences of anemia
- tissue hypoxia and necrosis
- blood osmolarity causing edema
- low blood viscosity
ABO Blood type is determined by the…
presence or absence of antigens
Blood type O has which antigens?
Neither A or B
Antigens are…
-complex molecules on the surface of a cell membrane that is unique to the
individual
-Determine the blood type
Antibodies are…
proteins secreted by plasma cells (gamma globulins)
Agglutination causes
clumping of RBCs. Happens when wrong types of blood mix.
Universal Donor
O-negative. Missing antigens
Universal Recipient
type AB- rarest
Antibodies for type A
Anti-B, same for other blood types
Leukocytes are
White Blood Cells
WBCs are split into two groups
- granulocytes
- agranulocytes
Granules have
lysosomes
Types of Granulocytes
- neutrophils
- eosinophils
- basophiles
Types of Agranulocytes
- lymphocytes
- monocytes
Neutrophils fight off
bacteria. phagocotize bacteria.
Eosinophils are increased in
parasitic infections, collagen diseases, allergies, and diseases of the spleen and CNS
Basophils increase in numbers in
chicken pox, sinusitis,
Agranulocytes are involved in
immunity, have an anti cancer job
Lymphocytes secrete
antibodies and provide immunity