Class 6 Flashcards
Neoplasm
Uncontrolled cell growth
Cell differentiation
Become specialized
Autonomous neoplastic cell proliferation
independent of normal growth factors
Excessive neoplastic cell proliferation
No response to normal regulators
Disorganized neoplastic cell proliferation
disorganized compared to formation of normal tissues
Benign tumor
limited, slower growth
Malignant
more growth, poor outcome
Benign tumor macroscopic feature
Sharply demarcated
Encapsulated CT tissue
Benign tumor microscopic feature
Cells are similar
Benign tumor cellular feature
Uniform cell populations,
regular shape and size
Benign tumor chromosomal features
Normal chromosome numbers
Benign tumor biological features
Normal complex functions
Malignant tumor macroscopic features
No clear border or encapsulation
Malignant tumor macroscopic features (2)
Look different, unspecialized
anaplasia
backwards growth - specialized to unspecialized
