Class 5 Flashcards
SLE causes
Overprod. of antibodies
(SLE) Overprod. of antibodies causes
damage by attaching to own proteins
Primary immunodeficiency is
Congenital
Secondary immunodeficiency is
Due to infections, disease, etc.
ID disease characterized by
lymphopenia (low lymphocyte count)
Primary ID Disorders affect
Differentiation/maturation of T and B cells
DiGeorges Syndrome
Primary ID disorder
how AIDS virus affects over time
reduce immune system effectiveness
HIV mainly attacks
T Helper cells (CD4)
HIV results in
Inability to defend against infections
Phase of acute illness (Group 1) (HIV)
symptoms 3-6 weeks after exposure, lasting 2-3 weeks
Group 1 (HIV) symptoms
fever, night sweats, nausea, etc.
Phase of asymptomatic infections Group 2 (HIV)
Months to years, asymptomatic
Phase of generalized lymphadenopathy (Group 3)
Develops persistently early in disease
AIDS (Group 4)
Pt shows signs of aids – opportunistic disorders
Lymph nodes and AIDS
Causes enlargement
Brain and AIDS
nodules form, may destroy part of brain
Respiratory tract and AIDS
Local to URT progresses to LRT
GI tract and AIDS
Infections include parasites
Skin and AIDS
Dermatitis, infections
Tumours and AIDS
Lead to mortality (Kaposi’s Sarcoma)
Kaposi’s Sarcoma
caused by herpes, malignant disease endothelial cells
Amyloidosis caused by
Deposition of fibrillar substance
Amyloid deposited in
extra-cellular spaces
Amyloidosis results in
atrophy and loss of cell function
Amyloid is…
Fibrillar protein forming beta-pleated sheet
