Class 5 Flashcards

1
Q

SLE causes

A

Overprod. of antibodies

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2
Q

(SLE) Overprod. of antibodies causes

A

damage by attaching to own proteins

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3
Q

Primary immunodeficiency is

A

Congenital

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4
Q

Secondary immunodeficiency is

A

Due to infections, disease, etc.

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5
Q

ID disease characterized by

A

lymphopenia (low lymphocyte count)

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6
Q

Primary ID Disorders affect

A

Differentiation/maturation of T and B cells

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7
Q

DiGeorges Syndrome

A

Primary ID disorder

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8
Q

how AIDS virus affects over time

A

reduce immune system effectiveness

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9
Q

HIV mainly attacks

A

T Helper cells (CD4)

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10
Q

HIV results in

A

Inability to defend against infections

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11
Q

Phase of acute illness (Group 1) (HIV)

A

symptoms 3-6 weeks after exposure, lasting 2-3 weeks

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12
Q

Group 1 (HIV) symptoms

A

fever, night sweats, nausea, etc.

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13
Q

Phase of asymptomatic infections Group 2 (HIV)

A

Months to years, asymptomatic

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14
Q

Phase of generalized lymphadenopathy (Group 3)

A

Develops persistently early in disease

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15
Q

AIDS (Group 4)

A

Pt shows signs of aids – opportunistic disorders

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16
Q

Lymph nodes and AIDS

A

Causes enlargement

17
Q

Brain and AIDS

A

nodules form, may destroy part of brain

18
Q

Respiratory tract and AIDS

A

Local to URT progresses to LRT

19
Q

GI tract and AIDS

A

Infections include parasites

20
Q

Skin and AIDS

A

Dermatitis, infections

21
Q

Tumours and AIDS

A

Lead to mortality (Kaposi’s Sarcoma)

22
Q

Kaposi’s Sarcoma

A

caused by herpes, malignant disease endothelial cells

23
Q

Amyloidosis caused by

A

Deposition of fibrillar substance

24
Q

Amyloid deposited in

A

extra-cellular spaces

25
Q

Amyloidosis results in

A

atrophy and loss of cell function

26
Q

Amyloid is…

A

Fibrillar protein forming beta-pleated sheet