Chronic COPD- SAMA DI Flashcards
1
Q
SAMA used in COPD
A
Ipratropium bromide
2
Q
SAMA MoA
A
Block the bronchodilator effects of ACh on the M3 muscarinic receptors expressed in the airway smooth muscle
3
Q
SAMA ADEs
A
Dry mouth, cough, nausea, blurred vision, reports of glaucoma with face mask use
Also has ACh effects but poor systemic absorption limits them
4
Q
SAMA duration of effect
A
May be apparent 8 hours post-administration
5
Q
Ipratropium duration of action
A
6-9 hours
6
Q
Do SAMAs have good systemic absortption?
A
No
