Chronic Asthma- LAMA DI Flashcards

1
Q

LAMA

A

Tiotropium

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2
Q

LAMA MoA

A

Inhibits action of ACh at M3 muscarinic receptors in the bronchial smooth muscle –> bronchodilation

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3
Q

What are LAMAs used for in asthma therapy?

A

MAINTENANCE treatment

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4
Q

LAMAs in the GINA guidelines

A

May be beneficial to add on for still-uncontrolled asthma patients who are on a medium-high dose ICS/LABA combo (Step 4)

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5
Q

LAMA dosing for asthma vs. COPD

A

COPD dosing is 2x asthma dose

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