AR- Topical Decongestants

Question 1

Topical decongestants

Answer 1

Phenylephrine

Tetrahydrozoline

Naphazoline

Oxymetazoline

Question 2

Topical decongestants MoA

Answer 2

Target adrenergic receptors in the nasal mucosa to produce vasoconstriction and reduce swollen nasal mucous and improve ventilation

Question 3

Topical decongestant symptom target

Answer 3

Congestion

Question 4

Topical decongestant ADEs

Answer 4

Sneezing, burning, stinging, drying of nasal mucous

Question 5

Topical decongestants are applied where?

Answer 5

Directly to nasal mucosa

Question 6

Topical decongestants clinical pearls

Answer 6

Rapid onset of action
Limit use to ≤3 days or PRN to avoid rebound congestion

Question 7

Rebound congestion with a topical decongestant will happen when?

Answer 7

Prolonged use for >3-5 days