AR- Intranasal Antihistamines Flashcards
1
Q
Intranasal antihistamines
A
Azelastine
Olopatadine
Azelastine/fluticasone
2
Q
Intranasal antihistamines MoA
A
Competitively antagonizes histamine-1 receptors to prevent receptor activation
3
Q
Intranasal antihistamine symptom targets
A
Congestion, rhinorrhea, sneezing, nasal itching
4
Q
Intranasal antihistamine ADEs
A
Bitter taste, epistaxis, HA, somnolence, nasal burning
5
Q
Intranasal antihistamine onset of action
A
15-30 minutes
6
Q
Intranasal antihistamine delivery vs. OAH
A
More targeted; increased dosage to nasal tissue while limiting systemic effects
7
Q
Intranasal antihistamine vs. OAH
A
Equal or superior to OAH, can be effective in patients who fail an OAH
INAH > OAH for nasal congestion
