Chronic COPD- SABAs DI Flashcards
1
Q
SABAs used in COPD
A
albuterol, levalbuterol
2
Q
SABAs MoA
A
Relaxes airway smooth muscles by stimulating beta-2 adrenergic receptors, which increases cAMP and antagonizes bronchoconstriction → bronchodilation
3
Q
SABA ADEs
A
Tachycardia, tremor, hypokalemia, tachyphylaxis (more likely in elderly patients or with higher doses)
4
Q
SABA duration of action
A
4-6 hours (6-8 for nebulizer)
5
Q
SABA onset of action
A
5-15 minutes
6
Q
SABA recommended dosing frequency for COPD
A
PRN ATC
