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PHM 702- Asthma, Allergic Rhinitis, COPD > Chronic Asthma- Glucocorticoids DI > Flashcards

Chronic Asthma- Glucocorticoids DI Flashcards

1
Q

Glucocorticoids used in asthma

A

Prednisone and methylprednisolone

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2
Q

Glucocorticoids MoA

A

Improve receptor responsiveness to beta-2 adrenergic stimulation

Reduce mucus production and hypersecretion

Decrease BHR

Reduce airway edema

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3
Q

Glucocorticoids ADEs

A

Hyperglycemia
Increased appetite/weight gain
Insomnia/nervousness
Osteoporosis/fractures
Growth retardation
Immunosuppression
HPA axis suppression

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4
Q

When are glucocorticoids used in asthma treatment?

A

Severe asthma

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5
Q

Length of glucocorticoid therapy

A

5-7 days

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PHM 702- Asthma, Allergic Rhinitis, COPD (50 decks)

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