ChartsTablesEtc Flashcards
20kg animal (what re-breathing bag size)
2L
30kg animal (what re-breathing bag size)
3L
50kg animal (what re-breathing bag size)
5L
Calculation of therapeutic index
LD50/ED50
Xray
Advantages: fine resolution of hard surfaces; fast Disadvantages: less detail soft structures; radiation hazard
CT
Advantages: detail soft structures; lesions in 3D Disadvantages: radiation exposure risk
PET/SPECT
Advantages: image in vivo processes; high resolution soft tissue Disadvantage: requires short half-life radioisotopes; radiation risk
Ultrasound
Advantages: soft tissue abnormalities; may be used intravascularly Disadvantages: poor image quality; not quantifiable
Thermography
Advantages: non invasive, repeatable and quantifiable Disadvantages: low resolution; may be affected by environmental temperatures and animal factors
MRI
Advantages: good contrast and tissue distinction; no radiation Disadvantages: restrictive condition; metal safety hazards
Fluorescent imaging
Advantages: can track metabolic processes Disadvantages: time sensitive and requires chlorophyll free diet
Bioluinescence
Advantages: noninvasive; fast and high throughput imaging Disadvantages: requires genetic manipulation of animals; not quantifiable
Red blood tube stopper
no anticoagulant; serum
Lavender/purple blood tube stopper
EDTA; plasma
Light green blood tube stopper
heparin, plasma
Enteropathy
NHP; Bacterial
Life cycle of tapeworm Dipylidium caninum
Live cycle of liver fluke
Isograft (I)
a graft of tissue that is obtained from a donor geneticially identical to the recipient
allograft
a transplant from one individual to another of the same species with a different genotype
xenograft
a transplant from one species to a different species
nude mouse
lack of a thymus; does not produce t cells
SCID mouse
lacks both T and B cells
XID mouse
B cells are defective and some llneage B cells are missing altogether
Beige mouse
defective NK cells
Phases of antibody production
Lag, Log, Plateau, Decline
IgG
most abundant immunoglobulin in serum
IgM
Second most abundant type of serum antibodies
Also present in birds, reptiles, amphibians, fish
IgA
found in body screations
location of lymph nodes in the mouse
Dry Bulb Macro Temp
Mouse, rat, hamster, gerbil, guinea pig
20-26C
Dry Bulb Macro Temp
Rabbit
16-22C
Dry Bulb Macro Temp
Cat, dog, NHP
64-84
18-29C
Dry Bulb Macro Temp
Farm animals, poultry
61-81
16-27C
Which factor will has the greatest effect on the amount of dissolved oxygen in water?
temperature
What is the average life span of the rat?
2.5 to 3 years
Female rats usually have postpartum estrus within ____ hours of parturition.
48
An unusual behavior that may be noticed in approximately 20% of gerbils is:
seizures
The average life span of a gerbil is:
2-4 years
Which species is most likely to be used to study thermoregulation in the laboratory?
bats
What seasonal change does an adult ferret undergo?
Losing weight in the spring/summer during mating season and gaining weight back in the fall
What is a characteristic of Old World monkeys?
Short nose with downward pointing nostrils
What is the term for a neutered male sheep?
wether
Minimum space
Mice
Area 6-15 square inches
Height 5 inches
Minimum space
Rats
Area 17-70 square inches
Height 7 inches
Minimum space
Hamsters
Area 10-19 square inches
Height 6 inches
Minimum space
Guinea pigs
Area 60-101 square inches
Height 7 inches
Rabbit cage height
16 inches
Cat cage height
24 inches
what is not included in a study protocol?
the conclusions of the study
carcass fridge temperature
below 44.6F
Dog minimum floor space
To Calculate the minimum amount of floor space:
Measure the length of the dog in inches (from the tip of its nose to the base of its tail).
Add 6 inches to this length.
Square this sum (that is, multiply the above result by the same number).
Then divide the squared result by 144 to obtain the minimum amount of floor space in square feet.
The minimum interior height must be at least 6 inches higher than the head of the tallest dog in the enclosure when it is in a normal standing position.
According to the Guide, how often must the IACUC conduct the facility inspections and program review?
annually (whereas PHS requires every 6 months)
According to the PHS policy, IACUC-approved research projects must be reviewed how often?
every 3 years
How often does an institution need to resubmit an Animal Welfare Assurance if with PHS?
every 5 years
