Chapters 1-4 - Introduction Flashcards
oscillate constantly to maintain homeostasis
feedback loops
negative feedback blank input signal
decreases
positive feedback blank input signal
increases
law of mass action
when a reaction is at equilibrium, the ratio of the products and substrates remains constant
enzymes modify reactions in these two ways
lowering activation energy, increasing meeting of substrates
enzyme activity can be controlled by both blank and blank factors
organic, inorganic
inorganic factors do what to control the enzyme and an example is blank
alter the active site, charge
organic factors are like blank and they do what to control enzyme activity…. example) blank
additional substrates, remove atoms/groups during reactions, vitamins
blank modulators can also control enzyme activity such as blank and blank
chemical, temp, ph
why does temp control enzyme activity
increases activity until it is too high and denatures the enzyme
how pH controls enzyme activity
as pH approaches optimum for specific enzyme, activity increases but decreases when optimum pH is passed
the protein that breaks down proteins and is in stomach
pepsin
example is pepsin and catalyze same reaction, but in different optimum conditions
enzyme isoforms
kinase is what kind of chemical reaction
exchange with phosphate
phosphorylase is what kind of reaction
addition of phosphate
phosphatase is what kind of reaction
subtraction of phosphate
atp to power a reaction is called
ATPase
aerobic respiration is really blank and blank
glycolysis, oxidative phosphorylation
anaerobic respiration is really blank and blank
glycolysis, fermentation
what is nice about anaerobic respiration
pyruvate reverse reaction cannot happen once lactic acid is formed so the pyruvate can be used later
making glucose by splitting glycogen
glycogenolysis
glycogen is a storage blank in the blank and blank
polysaccharide, muscles, liver
making new glucose is called
gluconeogenesis
gluconeogenesis uses blank, blank and blank…. it is like blank when those materials are used
glycerol, amino acids, lactate, reverse glycolysis
why does excess glucose need to be stored
excess glucose would dehydrate you if it stays in the blood
lipid synthesis and glucose storage generally occurs where
smooth ER and cytosol
three steps of lipid synthesis
- glycerol is made from glycolysis
- two-carbon acetyl units from acetyl CoA form fatty acids
- 1 glycerol + 3 fatty acids = triglyceride
why is the long term storage molecule a lipid rather than a carbohydrate?
fats are non polar so water is not attracted which makes it so no dehydration occurs. If long term storage was in glycogen then one would retain too much water since it is a polar carbohydrate.
5 steps of protein synthesis
- gene activation
- transcription
- mRNA processing
- Translation
- Modification
glycolysis occurs where
cytosol
citric acid cycle and ETC occurs where
mitochondria
gene activation, transcription, and mRNA processing all occur where?
nucleus
translation and modification occur where
cytoplasm