Chapter Five- Integumentary System Flashcards
Melanocytes
Skin colour cells that produce and store the pigment melanin
Major functions of the skin
-protection
-prevention of water loss/ secretions
-temperature regulation
-metabolic regulation
-immune system
-sensory reception
Epidermis
Epithelial tissue
-stratified keratinized
-outer thinner layer squamous
Keratinocytes
Provide replacement stem cells and new keratinocytes to replace dead cells
-inhibits evaporation
Langerhan cells
Part of the immune response (phagocytosis)
-key part in epidermal cancer cells
-5%
-present in stratum spinosum and stratum granulosum
Merkell cells
Sensory cells
-sensitive to touch
-when compressed release chemicals that stimulate sensory nerve endings
Stratum bassale
Deepest layer of epidermis
-single layer and tightly attached to underlying basement membrane
-contains merkle cells, keratinocytes and melanocytes
Stratum spinostum
Second from deepest
-non dividing keratinocytes linked together by demosomes
-macrophages and langhern cells
Stratum Granolusm
Third from deepest
-contains keratonin granules
-keratinization begins taking place
Stratum Lucium
Second from top
-thin, translucent region
-only found in thick skin, palms of hand and soles of feet
-keratinocytes
-no nucleus
Stratum Corneum
Top layer
-no nucleus
-anucleate keratinized cells (corneocytes)
-no nutrients
-desmosome breaks down
Cytokeratins
The keratins found in epidermal cells of the skin
-give skin strength and makes it waterproof
Melanin
Accumulates around the nucleus and shields the DNA within the nucleus
Darkening of skin
Takes place by the melanin production, and exposure to ultraviolet light
Keratinization
Keratinocytes fill up with protein keratin
-become thinner and flatter
-becomes a tightly interlocked layer of keratin fibres
-fully keratinized cell is dead, but strong due to keratin
A fully keratinized cell is…
Dead (no nucleus or organelles)
-strong because it contains keratin
Thick skin versus thin skin
Based on number of strata in epidermis
Thick skin
all five epidermal strata
Thin skin
lacks the stratum lucidum (only four layers)
-hair follicles, sebaceous glands, swat glands
Hemoglobin
Oxygen-binding protein present within red blood cells
-bright red colour
Amount of melanin in the skin is determined by
Heredity and light exposure
Carotene
Yellow-orange pigment
-acquired by eating vegetables such as carrots, corn and squash
Albinism
Hair is white, skin is pale, irises of eyes are pink
-lack of melanin production
-inherited recessive condition
-melanocytes cannot produce melanin
Bronzing
Skin appears golden-brown, copper or bronze in colour
-glucocorticoid hormone deficiency in adrenal cortex
-Addison disease
Cyanosis
Skin appears bluish, due to oxygen deficiency in blood
-airway obstruction, respiratory arrest, cardiac arrest or cold weather