Chapter 85 - Splanchnic artery aneurysms Flashcards
First reported repair of splanchnic artery aneurysm
Kehr 1903
Ligation of proper hepatic artery aneurysm
Paul 1951 on splanchnic artery aneurysms
Ligation and revascularization of traumatic hepatic artery aneurysm
Debakey and Cooley 1953 on splanchnic artery aneurysm
Repair of mycotic SMA
Definition of splanchnic artery aneurysms
Aneurysms affecting celiac, SMA, IMA and branches
Splanchnic aneurysm Association with aortic, renal, iliac or LE, cerebral aneurysms
33%
Incidence of splanchnic aneurysm
0.1-2%
10% in elderly
Distribution of types of splanchnic aneurysm by prevalence
Splenic 60% Hepatic artery 20% SMA 6% Celiac 4% Gastric artery 4% Jejunal/ileal/colic 4% PDA 2% GDA 1.5% IMA < 1%
Causes of splanchnic aneurysms
1) atherosclerosis
2) medial degeneration
3) collagen vascular disease
4) FMD
5) infection/inflammatory
6) iatrogenic
Risk factors for splanchnic aneurysm
1) multiparity
2) portal hypertension
3) post transplant
4) celiac occlusive disease (GDA/PDA aneurysms)
Multiple splanchnic aneurysm potential systemic causes
1) von Recklinghausen disease
2) Ehlers-Danlos syndrome
3) periarteritis nodosa
4) Behcet disease
5) systemic arteritis
6) endocarditis with septic emboli
7) connective tissue disorders
8) excessive use of acetaminophen
Vaccination for post-splenectomy
1) Pneumococcal
2) Meningococcal
3) Haemophilus influenzae B
Splanchnic arteries that can be ligated in emergency
Splenic with splenectomy
proximal hepatic artery
PDA
gastric artery
SMA and celiac will need reconstruction or bowel resection of dead portions
Criteria to observe splanchnic artery aneurysms
1) less than 2cm
2) asymptomatic
3) minimal or no growth
Criteria to intervene on splanchnic artery aneurysms
1) women of child bearing age or are pregnant
2) pseudoaneurysms
3) SMA, GDA, PDA aneurysms
Methods of endovascular treatment of splanchnic aneurysm
1) nitinol coil, cyanoacrylate glue
2) particles or Gelfoam
3) covered stents
4) flow diverting stents
5) thrombin or ethyl alcohol injection
Down sides of endovascular treatment of splanchnic aneurysms
1) access related complication
2) contrast
3) end-organ embolization
4) higher rate of failure
5) prolonged surveillance
Mortality after endovascular treatment
8.3%
All related to emergent intervention with hemodynamic instability
Techniques for embolizing splanchnic aneurysms
End branches can be glued directly
For mid segments, distal coil, then glue or more coil, and proximal coil plug
Flow diverting stents
Non-covered stents geared to redirect flow away from the aneurysm itself without occluding branch vessels
Incidence of splenic artery aneurysm in general population
0.78%
Female:male 4:1
occur at younger age than other splanchnic aneurysms but still affects elderly more
Average size of splenic aneurysm at diagnosis and size at symptom onset
2cm at diagnosis
3cm with symptoms
Local of splenic aneurysm along splenic artery
1) Saccular
2) mid- or distal splenic artery and at bifurcations
Giant splenic artery aneurysm
> 10 cm more often in men
Cause of splenic artery aneurysm
1) atherosclerosis
2) FMD
3) arteritis
Parity association with splenic aneurysm
1) hormone, FMD, wall stress? etiology unclear
2) 50% of female with >6 preg have splenic aneurysm
3) 80% of female with splenic aneurysm had > 4.5 pregnancies
Incidence of splenic aneurysm in patients with portal HTN or cirrhosis waiting for liver transplant
10-50%
Causes of splenic artery PSEUDOaneurysm
1) trauma
2) infection
3) pancreatitis (diggest splenic artery)
Hemosuccus pancreaticus
rupture of visceral aneurysm into main pancreatic duct
% of splenic artery aneurysm rupture on presentation
10%
Rate of rupture of splenic artery aneurysm not during pregnancy
2%
Pregnancy rupture of splenic artery accounts for this % of all ruptures
50%
double rupture phenomenon of splenic artery aneurysm rupture
First into the lesser sac
tamponade up to 4 days
then free rupture into peritoneum
Mortality associated with splenic artery aneurysm rupture
10-25%
Mortality for maternal and fetal during splenic artery aneurysm rupture
75% mom
95% fetus
Rupture in pregnancy when does it occur
third trimester
Prevalence of splenic artery aneurysm in pregnant women
0.1%
How prevalent is portal hypertension in splenic artery aneurysm ruptures
20%
Indication to treat splenic artery aneurysms
1) Ruptures
2) symptomatic
3) women childbearing age
4) pseudoaneurysms
5) size > 2cm
Rate of splenic artery aneurysm growth
Most 90% do not grow
those that grow grow at 0.06-0.2 mm/year
Collateral to supply spleen without splenic artery
Short gastric vessels
Hepatic artery aneurysms first described by
Wilson 1809
ligated it in 1903
Hepatic artery aneurysms as a % of all splanchnic aneurysms
20%
Incidence of hepatic artery aneurysm
0.4%
Distribution of the hepatic artery aneurysms
Extrahepatic vasculature 75-80%
Extraparenchymal liver space 20%
Exlusively intrahepatic 5%
Distribution of hepatic artery aneurysm along the extrahepatic vasculature
1) CHA 63%
2) Right hepatic 28%
3) Left hepatic 5%
4) bilateral hepatic 4%
Association of hepatic artery aneurysm with sex and pregnancy
Male:Female 3:2
No association with pregnancy
Mean age of occurence without trauma of hepatic artery aneurysms
60 years
Most common cause of hepatic artery aneurysm
Atherosclerosis 30%
Comorbidities associated with hepatic artery aneurysm
1) HTN
2) arterial dysplasia
3) medial degeneration
4) trauma
5) polyarteritis nodosa
6) biliary disease
Rate of other splanchnic and nonsplanchnic aneurysms in the presence of hepatic artery aneurysm
20% splenic artery aneurysm
40% nonsplanchnic mostly aortic
Quincke’s triad
Rupture of hepatic aneurysm into bile ducts:
1) hemobilia
2) jaundice
3) RUQ pain
Mortality of hepatic artery aneurysm rupture
20-70%
Treatment of hepatic parenchyma aneurysms
Embolization and hepatic resection or lobectomy
Consequence of ligating right hepatic artery
Gallbladder necrosis
SMA aneurysm incidence
1 in 12000-19000
Where along SMA do aneurysms occur
first 5 cm
Causes of SMA aneurysms
1) Mycotic 60%
2) atherosclerosis
3) connective tissue disease
4) PAN
5) pancreatitis
6) trauma
Rupture rates for SMA aneurysms and mortality rate
Rupture 38-50%
Mortality 30-90%
Most common organism for mycotic SMA aneurysm
Streptococcus 47%
Staphylococcus 28%
SMA aneurysm symptoms
1) abdominal pain
2) nausea/vomiting
3) GI bleeding
mortality of SMA surgical repsair
15%
Indication to repair SMA aneurysms
1) Size > 2.5 cm
2) pseudoaneurysms
3) mycotic aneurysms
Celiac aneurysm as percentage of all splanchnic aneurysms
4%
Prevalence of celiac aneurysms
1 in 8000
Celiac aneurysm with concomitant splanchnic aneurysm or AAA
40% other splanchnic
20% AAA
Causes of celiac artery aneurysms
1) Atherosclerosis
2) infection 20%
Epidemiology of celiac artery aneurysms
1) male
2) 50-60’s of age
Celiac artery aneurysm rate of rupture and subsequent mortality
10-20% rupture
50% mortality if ruptured
Factors associated with celiac artery aneurysm rupture
none found
Consensus size for celiac artery aneurysm repair
2.5 cm
Rate of gastric and gastroepiploic aneurysms of all splanchnic artery aneurysms
4%
Causes of gastric/gastroepiploic aneurysms
1) Atherosclerosis 30%
2) trauma 25%
3) infection 15%
Epidemiology of gastric/gastroepiploic aneurysms
1) male
2) age 60-70
Ratio of aneurysms in the left/right gastric (lesser curvature) vs gastroepiploic (greater curvature)
10:1, more in gastric
Clinical presentation of gastric/gastroepiploic aneurysm
Rupture 90%
Mortality after rupture of gastric/gastroepiploic aneurysm
70%
GDA and PDA aneurysms as % of all sphlanchnic aneurysms
2% PDA
1.5% GDA
Ferguson 1895 on splanchnic aneurysms
First description of superior PDA aneurysm
Causes of GDA/PDA aneurysms
1) pancreatic pathology
2) celiac stenosis/occlusion
3) abdominal trauma
4) iatrogenic injury
Epidemiology of GDA/PDA aneurysms
Male: female 4:1
60’s age
Size of GDA/PDA aneurysm that predispose rupture
no evidence
% of patients with GDA/PDA aneurysms that present with rupture
65-75%
Mortality after GDA/PDA rupture
30-40%
Rate of IMA branch aneurysms of all splanchnic aneurysms
2%
Causes of IMA branch aneurysms
1) inflammation and infection accounts 1/3
IMA branch aneurysm epidemiology
5:1 male : female
Mortality after mesenteric branch aneurysm rupture
20%
Most common location of visceral venous aneurysms
1) main portal vein
2) junction of SMV and splenic vein
3) hepatic hilus