Chapter 24 - Radiation safety Flashcards
Classification of types of radiation
Nonionizing radiation = US, MR, laser, microwave Ionizing = X-ray, gamma rays, beta rays, electrons
Define Roentgens
measurement for amount of ionization that radiation produces in air Units = 1R = 2.58 x 10^-4 C/kg
Define Curie
Measurement of radioactivity Number of particles/sec from 1 g of radium
Define absorbed dose
Measure of amount of energy in medium by ionizing radiation per unit mass of matter Equal to amoun tof heat generated by radiation per tissue weight in specified material Unit = Gray = 1 J/kg = 100 rad (radiation absorbed dose)
Define Radiation weighting factor
degree of damage by different types of radiation
Define equivalent dose
Measure of radiation dose to tissue taking into account different types of radiation Absorbed dose x W(R) Unit = Sievert = 1 Gy x W = 100 rem (roentgen equivalent man)
Define effective dose
Taking into account of different sensitivity of tissue Tissue weighting factor WT Unit = Sievert = 1 Gy x W = 100 rem (roentgen equivalent man)
Define tissue weighting factor
sensitivity of each tissue type to damage
Weighting factor
combines WR with WT
Two types of effects of radiation on biological tissue
1) Deterministic effects 2) stochastic effects
Define deterministic effects
1) dose-dependent cell death 2) hair follicle, skin, subcu tissue, lens of eye 3) acute events 4) threshold level exceeded 5) higher dose, greater injury
Threshold effective dose for various organs and damages
TABLE 24.2
Acute whole body exposure and consequences of radiation
10-20 Gy high energy = death 0.5-1 Sv = light radiation sickness 1Sv = slight blood changes 2-3 Sv = nausea, hair loss, hemorrhage 3Sv = death in 50% in 30 days > 6Sv = unlikely survival
Define stochastic effects
1) aka probabilistic effects 2) DNA damage to single cells = mutation 3) all-or-none phenomenon 4) probability of occurrence increasing as cumulative radiation exposure increases 5) no established threshold level 6) linear-nonthreshold model of incremental risk
Probability of fatal cancer as result of radiation exposure
4% per 1Sv of lifetime dose 0.004%/mSv < 100 mSv does not cause cancer