Chapter 102 - Compartment syndrome and its management Flashcards
Poiseuille’s Law
F = pi r^4 deltaP / 8nL F = capillary blood flow r = radius of capillary deltaP = pressure gradient pre-capillary arteriole to post-capillary venule
Matson’s critical closing pressure theory
Capillaries collapse after this pressure Disproven by Hartsock
Hartsock dynamic pressure ICP-MAP cutoff for likely capillary collapse
25.5 +/- 14 mmHg
Dynamic intracompartmental pressure threshold for 1) healthy tissue 2) injured tissue
MAP - ICP 1) < 30 mmHg 2) < 40 mmHg
Usual cutoff used for pressure threshold
MAP - ICP < 40 mmHg DBP - ICP < 10 mmHg
Causes of compartment syndrome
1) ischemia reperfusion 2) trauma 3) venous outflow obstruction (needs extensive multilevel DVT) 4) hemorrhage 5) fractures 6) crush injuries 7) iatrogenic
Mechanism of ischemia reperfusion leading to compartment syndrome
1) muscle injury 2) increase microvascular permeability 3) efflux of plasma protein 4) interstitial edema
Papalambros risk factors of compartment after limb ischemia
1) prolonged > 6 houors 2) younger age 3) insufficienct collaterals 4) hypertension 5) acute course of occlusion 6) poor backbleeding from distal vessels
Rate of fasciotomy after different type of vascular trauma
1) Arterial: 29.5% 2) Venous: 15.2% 3) Combined arterial + venous: 31.6% 4) Popliteal artery injury: 61%
Rate of fracture-induced compartment syndrome
1-29%
Risk factors associated with fractures that predispose compartment syndrome
1) anterior compartment of leg 2) flexor compartment of arm 3) communited fracture (means higher energy of injury)
Mechanism that crush injuries cause compartment syndrome
1) direct muscle injury 2) ischemia reperfusion 3) large volume crystalloids
Iatrogenic causes of compartment syndrome
1) extravasation of IV 2) bleeding 3) compression
Secondary compartment syndrome define
1) no direct trauma 2) diffuse microvascular permeability due to trauma-induced SIRS 3) massive fluid resuscitation
Clinical presentation of compartment syndrome
1) pain out of proportion 2) Pain with passive motion of muscles in compartment 3) paresis/parasthesia 4) tense compartment
How good is clinical presentation in terms of positive predictor and negative predictor for compartment syndrome
Poor positive predictor 11-15% Great rule out test 97-98%
Normal range of compartment pressures
< 10-12 mmHg
When to measure compartment pressure
1) equivocal cases 2) unconscious patient 3) pediatric patient
Causes of hand compartment syndrome
1) crush 2) fracture
Number of compartments in the hand
10
Thigh compartment syndrome cuase
Blunt trauma, crush, contusions
Which thigh compartment most likely to get compartment syndrome
Anterior
Gluteal compartment syndrome causes
1) hypogastric ligation or embolization 2) hip arthroplasty 3) prolonged compression
Symptoms of gluteal compartment syndrome
1) rhabdomyolysis 2) renal failure 3) sciatic nerve palsy
Mars protocol for first aid to hypoxic cells
1) maintain normal BP 2) remove constricting bandages 3) maintain limb at heart level 4) O2 supplement