Chapter 8 - Diseases of the Blood, Heart and Blood Vessels Flashcards
The function of RBCs is what?
Carry oxygen to cells and tissues, and CO2 out of tissues
Function of WBCs
Inflammation, immunity
Platelets or Thrombocytes
are produced where?
In the red bone marrow
What is the function of Platelets ?
Blood Clotting
What are Leukocytes and what do they do?
Increase in number of WBC in blood. May be physiological or pathological
Abnormal reduction in number of WBC in blood?
Leukopenia
The Etiology of Leukopenia?
Radiation
Chemical Poison
Some infections
The definition of Anemia?
Decrease in the number of erythrocytes, hemoglobin or both resulting in decreased ability to carry oxygen to the body tissues
What is primary anemia?
Chronic, Hematologic disease
What is Secondary Anemia?
Develops as a complication of another disease; Non hematologic
What is happening in Increased Destruction Anemia?
RBCs are being destroyed
What is happening in Decreased Production Anemia?
Producing less RBCs than normal
Etiology of Increased Destruction Anemia (IDA) ?
Hemorrhage
Injury or Trauma
Genetic
Infections
The Primary disease of IDA
Sickle Cell Anemia
What does Sickle Cell Anemia do?
Genetic mutation results in hemoglobin S
Gives Tachycardia
Fatigue
Dyspnea
Erythroblastosis Fetalis (Primary)
Hemolytic disease of the newborn; Mother and baby have different Rh blood types
An overactive spleen due to mononucleosis or liver cancer
Hypersplenism
The Etiology of Decreased Production Anemia
Radiation Chemical Poisons Infection Metabolic Disorder Leukemia
What is Aplastic Anemia?
Damage to bone marrow of unknown origin
A B12 deficiency
Pernicious Anemia
A deficiency of B12 and folic acid
Megaloblastic anemia
Megablasts = large RBC
What are hemapoietic disorders associated with?
Formation of blood and blood components
What does Leukemia mean?
White Blood
Cancer of WBC producing structures
What is acute leukemia common in?
More common in children
Bone marrow makes too many RBCs causing thickening of blood
Polycythemia Vera
Erythrocytosis is what ?
Increase in RBCs
May result in Plethora
A severe decrease in the number of platelets?
Thrombocytopenia
What is Hemophilia?
X-linked or somatic inherited hemorrhagic disease
What does severe hemophilia cause?
Hemarthrosis (bleeding into joints)
What is Cardiac Dilatation?
Condition of the heart being enlarged
How is Cardiac Dilatation caused?
Blockage of thoracic aorta
Cardiac Hypertrophy does what?
The enlargement of the heart ventricles due to the increase in size of the myocardial cells
Hypertensive Heart Disease?
Due to uncontrolled high blood pressure
What is normal blood pressure?
120/80 mmHg
Benign Hypertension is what?
140/90
Malignant Hypertension?
160/110
Inflammation of the membrane covering the heart
Pericarditis
What is Myocarditis?
Inflammation of the muscular walls of the heart; Usually wall of left ventricle
Endocarditis?
Inflammation of the lining membrane of the heart
What is the failure of a heart valve to close completely?
Valvular Insufficiency
What is Rheumatic Heart disease?
Condition of permanent damage to heart valves
The Etiology of Coronary Artery Disease?
Atherosclerosis
Thrombus
Embolus
Spasms
Cardiac Failure is what?
Inability of the heart to supply adequate blood flow to peripheral tissues and organs
General weakening of the heart overtime, leads to heart failure
Congestive Heart Failure
What is another word for a heart attack
Myocardial Infarction
A disease or disorder of the heart?
Cardiomyopathy
Inflammation of the entire heart and its surrounding structures
Pancardidis
Patent Ductus Arteriosus is what?
Aorta and Pulmonary artery are connected to each other
Coarction of the Aorta ?
Constricted segment of the aorta, usually above the heart
Arteriosclerosis definition
Disease of the arteries results in thickening and loss of elasticity of the arterial walls
Atherosclerosis definition
Deposition of lipids in the inner layer of arterial wall
Aneurysm definition
Local dilation of the wall of blood vessel
Types of Aneurysms?
Saccular
Fusiform
Dissecting
Inflammation of a vein
Phlebitis
Varicose Veins?
Enlarged, tortous blood vessels
Prefix meaning Blood
Hem, Hemo
Hematesis
Vomiting of blood
Hematoma
Tumor like swelling of blood
Discharge of red blood cells in urine
Hematuria
Excessive and spontaneous bleeding
Hemophilia
Blood in Sputum?
Hemoptysis
Escape of blood in blood vascular system
Hemorrhage
Inflammation of the liver
Hepatitis
Protrusion of an organ from an abnormal opening
Hernia
Means dissimilar
Hetero
Means similar
Homeo
Abnormal collection of fluid in an cavity of the body
Hydrocele
Accumulation of cerebrospinal fluid in brain
Hydrocephalus
What is Hydronephrosis?
Distention of the pelvis and calyces of one or both kidneys with urine
Means above or excess
Hyper
Means deficiency or beneath
Hypo