Chapter 8 Flashcards
Describe the hypersensitivity reaction type 1 and give an example
Type 1: allergic anaphylactic
- mediates allergic inflammation
- IgE mediated
- ex: anaphylaxis
Describe the hypersensitivity reaction type 2 and give an example
Type 2: antibody
- immune response against antigens that are an integral part of the cell membrane and are usually associated with autoimmune disorders
- antibody-mediated (IGG or IGM)
- ex: blood transfusion reactions
Describe the hypersensitivity reaction type 3 and give an example
Type 3: immune complex
- mediated by immune complex and cause vasculitis
- ex: SLE
Describe the hypersensitivity reaction type 4 and give an example
type 4: delayed
- purely cell-mediated immune response associated with chronic inflammation
- ex: contact dermatitis
Define autoimmunity
disturbances in the immunologic tolerance and self-antigens
define alloimmunity
immune reaction to tissues of another individual (ex: transfusions)
What are the antigens for ABO blood group
A and B antigens
the sera of blood group O individuals contain ____ antibodies against ______ carbohydrates
a. IGA; A
b. IGG: complex
c. IGM; A and B
d. IGE; B
c. IGM; A and B
the sera of blood group______ individuals have IgM antibodies against the ______ antigen
a. B; B
b. A; B
c. A; A
d. O; A and B
b. A;B
The sera of group B have _____ antibodies against the ___antigen in their sera
a. IgM; A
b. IgG: B
c. IgG; O
d. IgG; AB
B. IgM; A
These individuals do not have antibodies to either A or B antigens.
a. type O
b. type B
c. type A
d. type AB
d. type AB
what is the RH blood group?
antigens expressed only in RBC’s
which blood type is the universal recipient? why?
type AB because they don’t have anti-B and anti-A
Which blood type is the Universal
Donor? Why?
Type O because they have no antigens. they won’t cause a reaction during transfusion
Tuberculosis (TB) skin test is an example of which type of hypersensitivity?
a. type 3
b. type 4
c. type 2
d. type 1
b. type 4
