Chapter 7 - Homeostasis Flashcards
Water loss
When we breathe out, sweat, in urine (produced by the kidneys) and ions in sweat and urine.
Hormones
Chemical substances that coordinate many bodily processes
Why we must keep our core temperature constant
So enzymes work at an optimum temperature, so we do not get hypothermia and our cells stop working.
Sugar levels
Sugar is the energy source for our cells, our sugar levels in the blood are controlled by the pancreas.
What is removed via the lungs
Carbon dioxide (when we breathe out)
Urea
Produced in the liver from the breakdown of amino acids and removed by the kidneys in the urine and temporarily stored in the bladder.
Liver
Excess amino acids changed to urea and amino group removed (deamination) which forms ammonia which is converted to urea, passed in the blood to the kidneys and excreted in urine.
In urine
Poisonous substances such as ethanol are detoxified and excreted in urine. Old red blood cells are broken down and the iron is stored to make new ones.
Selective reabsorption
Filtering the blood, reabsorption has the sugar, reabsorbing the dissolved ions needed by the body, reabsorbing water and releasing urea, excess ions and water in the urine.
ADH
Is released by the pituitary gland if the water content of the blood is too low. This causes the kidneys to reabsorb more water, making the blood concentration return to normal levels and resulting in more concentrated urine.
Low water content of blood
less ADH released into blood and less water reabsorbed in kidneys, resulting in more dilute urine.
Dialysis
Blood flows between partially permeable membranes and has the same concentration of useful substances as the patients blood.
Dialysis machine process
Arterial blood leaves arm ➡️ blood thinners prevent clotting ➡️ dialysis machine (waste and urea removed) ➡️ clean blood flows through bubble trap ➡️ clean blood returns to a vein in the arm
Advantages of dialysis
Access to medical support, no equipment needed at home, treatment performed for you.
Disadvantages of dialysis
Travelling to centre 3 times a week, takes 8 hours, limiting fluid intake and risk of infection.
Rejection of kidneys (transplanted)
Antigens on donor organ different, antibodies of recipients immune system attack antigens, kidney is rejected. Immunosuppressant drugs can prevent it.
Advantages of kidney transplants
Closer than dialysis to having own kidney, fewer diet and fluid restrictions and more energy.
Disadvantages of kidney transplants
Rejection, daily medication, susceptible to infection and risks associated with major surgery.
Thermoregatory centre
In hypothalamus, has receptors detecting temp of blood flowing through brain.
Cooling down
Blood vessels supplying blood to the surface of the skin dilate so more blood flows through the capillaries. Skin flushes, heat energy lost by radiation. Hair lies flat (less air trapped) and rate of sweating increases and water evaporates from skin, taking heat energy from blood.
Warming up
Blood vessels constrict, reduces blood through capillaries near surface of skin, reduces energy released by radiation at surface of skin. Muscles contract and relax rapidly - shivering requires respiration which releases energy and raises temp. Less sweating.
High glucose levels
Insulin produced, moves glucose into cells. In liver and muscles, excess glucose converted to glycogen for storage. When full is stored as a lipid.
Homeostasis
The process by which our body maintains a constant internal environment. Controls water content, ion content, temperature and blood sugar level.
Low glucose levels
Pancreas releases glucagon, causing glycogen in liver to change to glucose which is released back into blood.
Type 1 diabetes
Little insulin produced by pancreas, blood glucose level v high. Controlled by restricted diet.
Type 2 diabetes
Body does not respond to insulin, controlled by diet, exercise and drugs.
Treating type 1 diabetes
Pancreatic transplants, using embryonic stem cells to produce insulin secreting cells.
Treating type 2 diabetes
Balanced diet, weight loss, regular exercise and drugs to help insulin work on body cells.