Chapter 5 - Viruses Flashcards
virion
a mature virus. the infective form of a virus.
what does it mean to be enveloped?
coated with host cell membrane components
ubiquitous
present, appearing, found everywhere
what is an interferon?
proteins made and released by host cells in response to the presence of pathogens such as viruses
describe viruses (5 points)
- immunosuppressive
- genetically unstable entities
- sensitive to interferon
- chemotherapeutants difficult
- maintain virulence if passed through animals
virulence
the relative ability f a microorganism to cause disease
what is the difference between in vivo and in vitro?
vivo: studies conducted on living organisms in their normal intact state
vitro: studies conducted using components of an organism that have been isolated from their usual biological surroundings (test-tube experiments)
the 4 fates of viral invasions inside cell:
- Lytic (acute)
- Persistant (chronic)
- Latent
- Abortive
what does LYTIC mean, when referred to fate of viral invasions inside cell?
many viral progeny in a short period, host cell dies
what does PERSISTANT mean when referred to fate of viral invasions inside cell?
few too many viral progeny over long time, host cell survives, but damaged
what does LATENT mean when referred to fate of viral invasions inside cell?
no viral progeny, but can become productive later
what does ABORTIVE mean when referred to fate of viral invasions inside cell?
genome enters cell, but no viral progeny produced (cell is RESISTANT)
name three types of viral reproduction
- general
- lytic (non-enveloped)
- budding (enveloped)
what are the five stages of diagnosis?
- observation: behaviour, external lesions, pathology
- microscopy: EM
- live cell culture: CPE (CHSE, SHK, RTG, FHM, SSN-1, EPC)
- serological tests: (ELISA, IFAT, FAT)
- genetic: (PCR, RT-PCR)
Chemotherapeutics: what kind?
none.
only disinfectants:
- virkon
- peroxiguard
- Water sterilization (UV or Ozone)
