Chapter 46 Diabetes Flashcards
______ cells secrete insulin —> lowers blood glucose
beta
________ cells secrete glucagon —> raises blood glucose
alpha
_____ cells secrete somatostatin
Delta
The hallmark sign of Diabetes Mellitus is elevated ________ ________ levels. DM is the leading cause of non-traumatic amputations, blindness, and end-stage renal disease
glucose levels
Type 1 diabetes is characterized by the destruction of the pancreatic ______ cells
beta
Type 2 diabetes is characterized by impaired insulin _____________ and insulin ______________
secretion
resistance
Patients with T1DM have to take life long _________ because their pancreas is not making any
insulin
Diabetic Ketoacidosis occurs due to a deficit of ________ resulting in disorders in the metabolism of carbs, proteins, and fats
insulin
Causes of DKA (4)
Sepsis
Stress
Skipping Insulin
Surgery
What are the manifestations of DKA? 4Ks
Ketonuria
Decreased K+
Ketotic breath (sweet smell)
Kussmaul Respirations (deep rapid breathing)
Type 2 diabetes is due to the decreases sensitivity to insulin or decreased insulin ____________
production
What is the first line of treatment for type 2 diabetes?
Diet and exercise
Insulin resistance and impaired insulin secretion are the main causes of type ____ diabetes
2
DKA is super rare in Type ___ diabetes
2
T2DM Clinical Manifestations (3Ps)
polyuria — large amount of dilute urine
polydipsia — excessive, abnormal thirst
polyphagia — extreme hunger
HHNS stands for:
Hyperglycemic Hyperosmolar Non-ketonic Syndrome
HHNS is a complication of T_DM. It included Hyperosmolality and hyperglycemia with alterations in LOC.
2
HHNS is ______ blood sugar. The blood sugar is greater than >_____
high
600
Osmolarity causes a build up of glucose, sodium and other substances into the blood, pulling fluid from other parts of the body (True or false)
true
Diabetic ketoacidosis if a higher sugar of _____ and higher
250
The four K’s of DKA is:
Ketonuria
Decreased K+
Ketotic breath (sweet smell)
Kussmal respirations (deep breathing
Meticulous _____ care is very important for patient education for diabetes
foot