Chapter 45 Endocrine Flashcards
Negative Feedback is where an increase of a hormone causes ______ to be produced and a decrease in hormone causes ________ to be produced
less
more
The endocrine system is a ____________ feedback system
negative
Endocrine disorders are caused by a __________________ or ________________ of hormones
overproduction or underproduction
**Diagnostic tests for hormone levels
* Blood and _______
*S___________ or S____________ testing
* Genetics
* Radiology including
**P___ and Dexa— measures bone mineral density
urine
Stimulation, suppression
PET
The ________ gland is referred to as the “master gland”; it secretes hormones into the bloodstream
Pituitary
The _____________ is the coordinating center of the brain
Hypothalamus
Suppression tests are used to detect ____________ of an endocrine organ
HYPERsecretion
What are the hormones that the anterior pituitary gland secretes: 6
Follicle Stimulating Hormone
Lutenizing Hormone
Adrenocorticotropic Hormone
Thyroid Stimulating Hormone
Prolactin
Growth Hormone
What are the hormones that the posterior pituitary secretes:
Antidiuretic Hormone
Oxytocin
Too much GH can cause what?
Gigantism (before puberty) or Acromegaly (after puberty/ adult)
Hyperpituitarism is most often caused by what ?
Tumors or hyperplasia
- Increased Growth Hormone causes :
- Increased ACTH causes:
- Increased TSH causes:
- Increased ADH causes:
Gigantism/Acromegaly
Cushing’s
HYPERthyroidism
SIADH
- Decreased Growth Hormone causes :
- Decreased ACTH causes:
- Decreased TSH causes:
- Decreased ADH causes:
Dwarfism
Addison
HYPOthyroidism
DI
_________ therapy may be used alone or in combination with surgery and or radiation
Drug
____________ removal of the pituitary gland and tumor, called ______________ is the most common treatment for hyperpituitarism
Surgical, hypophysectomy
Immediately after surgery, advise pt to avoid activities that increase ICP such as:
Brushing teeth (2weeks)
Bending over
Straining
Coughing
Blowing nose
What is the most common surgical method for a hypophysectomy?
Oronasal transsphenoidal approach
Nursing Interventions post Hypophysectomy
Q___H Neuro Checks
Assess for ___________drip and assess drainage for ___________
Elevate _____
Avoid __________ and ___________ ________
Assess for meningitis
____________ replacement
Avoid bending/ straining/ brushing teeth
Education: decreased sense of ________
1
postnasal , glucose
HOB
coughing, blowing nose
Hormone
Smell
Growth Hormone is regulated by the ________________ based on __________
hypothalamus
glucose
an _________ in BS causes the release of GH
a _____________ in BS inhibits release of GH
increase
decrease
______________ occurs if tumor formation is pre-puberty (rapid growth)
_____________ occurs if tumor formation is after puberty (in adult)
Gigantism
Acromegaly
Common Manifestations of TOO MUCH GH
* HA and _______ changes (r/t compression of optic nerve)
* Widened _________ bone
* Growth and thickening of ______, _______, _______.
* HTN, HF, CAD, _____________ (enlargement of organs)
* ______glycemia
visual
brow
hands, face, feet
organomegaly
HYPER
What is administered for Acromegaly/ Gigantism?
Somatostatin analogs (synthetic somatostatin) I — inhibits the release of GH
The thyroid gland is stimulated by the __________ ____________ gland
anterior pituitary
TSH controls the release of :
T3, T4
The thyroid gland produces 3 hormones, they are:
T3
T4
Calcitonin
______________ decreased serum calcium by increasing its deposition in the bone
Calcitonin
The _____________ gland produces the parathormone
Parathyroid
__________________ increases bone breakdown and increases serum calcium
Parathormone
What is the most common cause of Hyperthyroidism?
Grave’s disease : autoimmune disorder that produces thyroid stimulating immunoglobulins
What are the most common manifestations of Hyperthyroidism? 9
High metabolic rate
Increase temp, SBP, HR
Cardiac dysrhythmias
Goiter
Weight loss
Heat intolerance
Exopthalmos
What is the most common treatment for hyperthyroidism?
Radioactive Iodine (common to especially for Graves’ disease)
** some radioactivity is present in the patient’s body fluids and stool