Chapter 28: Hematologic Assessment Flashcards

1
Q

The Hematological System consists of the _______ and the blood forming _______, including the bone ______ and the reticuloendothelial system (RES)

A

blood
sites
marrow

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2
Q

Blood consists of _____ and ________ _______

A

plasma : fluid portion of blood
Blood cells : erythrocytes (RBC), leukocytes (WBC), thrombocytes (platelets)

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3
Q

Hematopoiesis is ______ cell and ___________ formation and ___________. It is important to balance for oxygenation, prevention of blood conditions.

A

blood
platelet
maturation

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4
Q

Blood components are made within the _____ _______

A

bone marrow

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5
Q

Plasma is the ________ portion of blood

A

fluid

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6
Q

Plasma plays a big role on impacting _________ balance

A

fluid

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7
Q

Red blood cells are also called:

A

Erythrocytes

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8
Q

Hemoglobin is where ________ binds to

A

oxygen

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9
Q

Reticulocytes are ______________RBCs. They are secreted when no ___________ is available — they won’t work as great as hemoglobin but is better than nothing

A

immature
hemoglobin

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10
Q

Erythropoiesis is the production of ______

A

RBCs

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11
Q

Iron stores and metabolism occurs in _______

A

RBCs

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12
Q

RBCs produce _______. This carries O2 from the _______ and delivers it throughout the body

A

heme
lungs

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13
Q

RBCs acts as a _________ to maintain acid/base __________

A

buffer
balance

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14
Q

RBC growth factor is known as :

A

Erythropoietin

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15
Q

White blood cells are also known as :

A

Leukocytes

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16
Q

WBCs provides protection by __________ and _________ properties

A

immunity
inflammation

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17
Q

Granulocytes are :

A

WBCs

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18
Q

Types of granulocytes include: E__________, B___________, N__________

A

eosinophils
basophils
neutrophils

19
Q

Bands are immature ___________. If the body is low on WBCs, ________ will be sent out

A

neutrophils
bands

20
Q

Agranulocytes are a type of:

21
Q

Types of agranulocytes are M_________, and L__________

A

Monocytes : “take out the trash” keeps everything nice and clean
Lymphocytes : T cells and B cells

22
Q

Platelets are also known as :

A

thrombocytes

23
Q

Platelets are made up of T_______________ and F_______

A

thrombopoietin
fibrin

24
Q

Fibrin is made of a _____________ protein that is like a “_____” that hold the platelets together for blood to stick together and form a clot

A

filamentous
mesh

25
Platelets are important for _______ ___________ and are stored in the _____ and are released as the are needed
blood clotting liver
26
_____% of platelets circulate and ____% is stored in the liver/spleen
80 20
27
what is the normal range for WBC?
4.5-11 X 10^9/L
28
What is the normal range of hemoglobin?
12-17g/dL
29
What is the normal range for platelets?
150,000-450,000/mm^3
30
What does an increased RBC mean?
Dehydration Hyperactivity of bone marrow
31
What does a decreased RBC mean?
Fluid volume overload Hemorrhage Anemia Renal disease
32
What does an increased Hemoglobin mean?
Dehydration
33
What does a decreased hemoglobin mean?
fluid retention anemia hemorrhage
34
What does an increased hematocrit mean?
dehydration low o2 availability
35
What does a decreased Hct mean?
fluid retention anemia hemorrhage
36
what does an increased WBC count mean ?
current or recent infection inflammation
37
What does a decreased WBC count mean?
immunosuppression
38
What does an increased platelet count mean?
certain cancers infection
39
what does a decreased platelet count mean?
decreased platelets —> bleeding
40
Hemostasis is the normal blood __________ mechanism to minimize ______ loss after injury
clotting blood
41
4 components of normal hemostasis * ___________ response (spasms/constricts to limit blood loss) * ________ plug formation * Development of _______ clot on platelet plug by plasma clotting factors * _______ of clot
Vascular Platelet Fibrin Lysis
42
What are the most commonly known hematologist studies?
CBC PT (prothrombin time) INR (international normalized ratio) aPTT (partial thromboplastin time) — done during HEPARIN dosing ** PT and INR are tested during COUMADIN and WARFARIN dosing
43
Complications of blood donation and transfusion * _______ hemolytic reaction * ______ hemolytic reaction * __________ reaction * __________ associated circulatory overload (TACO) * ___________ contamination * Transfusion related acute _______ injury (TRALI) *Delayed __________ reaction *Disease Acquisition Bleeding at site Tachy Hypotension fainting Syncope
acute febrile allergic transfusion bacterial lung hemolytic
44
Response to blood donation / blood transfusion complications ** Febrile Hemolytic Reaction Give _____________ medication to prevent fever ** Acute Hemolytic Reaction ____________ transfusion immediately ** Allergic reaction Give patient ______________ or _____________ can reduce risk of allergic reaction. For severe reactions — future blood components are washed out to remove any remaining plasma ________ **Transfusion Associated Circulatory Overload MILD— ______ rate of infusion and administer _________. SEVERE— Place patient _______, discontinue transfusion, notify _______. Oxygen and _______ may be needed to treat severe dyspnea ** Bacterial contamination If contam. occurs before transfusion is complete, _________ transfusion. Broad spectrum ____________ are used to prevent sepsis. If sepsis occurs, treat with fluids and IV ___________, corticosteroids, and vasopressors are after necessary ** Transfusion related acute lung injury (TRALI) Oxygenation, ___________, and fluid support ** Delayed Hemolytic Response Mild and requires _____ intervention
antipyretic discontinue antihistamines , corticosteroids, proteins slow, diuretics, upright, doctor, morphine discontinue, antibiotics, antibiotics intubation no