Chapter 20-Nervous System Flashcards
blood brain barrier
Blood vessels around the brain composed of endothelial cells packed so tightly that nothing can pass
axenic
devoid of microorganisms
bacterial meningitis
inflammation of the meninges
bacterial meningitis most common causative agents
Neisseria mengitidis, Streptococcus pneumoniae, Haemophilus influenzae, Listeria monocytogenes, Streptococcus agalactiae
Neisseria mengitidis
scariest causative agent of bacterial meningitis, there is a vaccine for this, acquire from inhalation
Streptococcus pneumoniae
causative agent of bacterial meningitis, acquired by inhalation, there is a vaccine
Haemophilus influenzae
causative agent of bacterial meningitis, acquired by inhalation, there is a vaccine
Listeria monocytogenes
causative agent of bacterial meningitis, acquired by contaminated food
Streptococcus agalactiae
causative agent of bacterial meningitis, acquired during birth
bacteremia
bacteria in the blood
Signs and symptoms of bacterial meningitis
fever (sign) and stiff neck (symptom)
treatment of bacterial meningitis
vaccines and antibiotics
Meningoencephalitis
chews up brain, caused by protozoans and amoebas
Naegleria fowleri
causative agent of meningoencephalitis, enters through nasal mucosa
Acanthamoeba
causative agent of meningoencephalitis, enters through conjunctiva and broken skin
Leprosy (Hansen’s Disease) types
tuberculoid and lepromatous
Tuberculoid type of leprosy
does not spread, numb lesions on skin
lepromatous type of leprosy
spreads, destructive deformities
Leprosy causative agent
Mycobacterium leprae
Mycobacterium leprae
causative agent of leprosy, Gram + bacillus, very slow growing, armadillo food pads, takes 20 years to show up for both types
Leprosy
infects peripheral nerves, skin cells; prefers outer extremities
signs and symptoms of leprosy
numbness, numb patches on skin
Botulism
paralysis, affects nervous system, prevents muscle contraction
Causative agent of botulism
Clostridium botulinum
Clostridium botulinum
causative agent of botulism, Gram +, anaerobic rod, spore forming
virulence factor of botulism
botulin toxin, most lethal toxin
3 types of botulism
food-borne, infant, and wound
treatment of botulism
antitoxin (immunoglobulin)
Tetanus causative agent
Clostridium tetani
Clostridium tetani
causative agent of tetanus, Gram +, anaerobic rod
virulence factor of tetanus
tetanospasmin (toxin)
signs and symptoms of tetanus
lock jaw, muscle spasms; prevents muscle relaxation
treatment of tetanus
DTP vaccine, immunoglobulins
Poliomyelitis (Polio)
paralysis of the lower extremeties
Polio causative agent
Poliovirus
Transmission of polio
contaminated water
types of polio
nonparalytic and paralytic
nonparalytic polio signs and symptoms
sore throat and back pain
paralytic polio signs and symptoms
paralysis of limb muscles or respiratory muscles
treatment of polio
vaccines; live and killed (live banned in US)
Rabies
zoonotic disease
rabies causative agent
Lyssavirus (ssRNA virus)
transmission of rabies
scratch or bite of infected animal
reservoirs of rabies
dogs, cats, skunks, bats, foxes
signs and symptoms of rabies
hallucination, hydrophobia, seizures, can’t swallow (causes foaming)
treatment of rabies
vaccine (on days 0, 3, 7, and 14)