Chapter 20 Flashcards

1
Q

What does a Bacteriostatic drug do? What is an example of one?

A

Inhibits; Tetracycline

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2
Q

What does a Bactericidal drug do? What is an example of one?

A

Lethal (kills); Penicillin

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3
Q

What is vancomycin used to treat?

A

MRSA; bactericidal drug that inhibits cell wall synthesis

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4
Q

Penicillin has __ rings.

A

2

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5
Q

What does quinolone antibiotics do?

A

they act by interrupting the replication of DNA molecules in bacteria; this involves inhibition of the bacteria’s gyrase.

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6
Q

What is an example of a drug that inhibits cell wall synthesis?

A

Penicillin cephalosporin

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7
Q

What is an example of a drug that inhibits protein synthesis?

A

Tetracycline

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8
Q

What is an example of a drug that injures the plasma membrane?

A

Nystatin (antifungals)

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9
Q

What is an example of a drug that inhibits nucleic acid synthesis?

A

Quinolone, Ciproflaxin

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10
Q

What is an example of a drug that inhibits enzymatic activity?

A

Acylovir (used to treat herpes)

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11
Q

What is Rifampin?

A

A bacteriostatic (inhibitory) drug used to treat TB

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12
Q

What is Quinolones?

A

a bactericidal drug that inhibits DNA synthesis and is used to treat UTI’s.

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13
Q

What is Amphoterecin-B?

A

an antifungal drug used to treat Histoplasmosis, Blastomycosis, Coccidiomyces

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14
Q

What 3 drugs can be used to treat ringworm?

A

miconazole, ketoconazole, griseofulvin

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15
Q

After how many days of illness will an antiviral drug be ineffective?

A

2 days

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16
Q

What are 4 antiviral drugs?

A
  1. Amantidine (Tamiflu)
  2. Acyclovir (herpes)
  3. AZT (HIV-AIDS)
  4. Gamicyclovir
17
Q

What are two antiprotozoan drugs?

A
  1. Chloroquine (for malaria)

2. Metronidazole (for trichomonas vaginalis)

18
Q

What are two antimicrobial susceptibility tests?

A
  1. Disc diffusion method (Kirby-Bauer)

2. Broth Dilution method (MIC, MBC)

19
Q

What are some things that can lead to drug resistance?

A

R-factor transfer, animal feed to R-strains developments, incomplete course of medicine, low doses, mutation in bacteria-drug binding sites

20
Q

What 2 drugs are in a synergistic combination?

A
  1. penicillin

2. streptomycin

21
Q

What 2 drugs are in an antagonistic combination?

A
  1. Penicillin

2. Tetracycline