Chapter 18

Question 1

Antigenic Determinants are _________.

Answer 1

Epitopes

Question 2

What are Toxoids made from?

Answer 2

exotoxins diphtheria and tetanus

Question 3

In the Hep B vaccine you are getting __ protein of the virus.

Answer 3

1

Question 4

What was different about the old pertussis vaccine?

Answer 4

It used the whole capsule; had many side effects; lasted longer

Question 5

The tuberculosis test is done by DTH which stands for?

Answer 5

delayed type hypersensitivity

Question 6

Name 6 serologic tests.

Answer 6

1. Precipitation RXN
2. Immunodiffusion test
3. Agglutination RXN
4. Neutralization RXN
5. Fluorescent antibody test
6. Enzyme linked Immunosorbent Assay (ELISA test)

Question 7

Precipitation RXN’s

Answer 7

IgM or IgG; soluble antigen; can tell if you have hep B antibody

Question 8

Immunodiffusion test

Answer 8

soluble antigen

Question 9

Agglutination RXN (blood typing)

Answer 9

involves 3 tests:

1. direct agglutination rxn
2. Indirect (passive) agglutination test
3. Hemagglutination test

Question 10

Neutralization Rxn

Answer 10

Involves 2 tests:

1. toxin neutralization test
2. virus neutralization test

Question 11

Fluorescent Antibody Test

Answer 11

A test in which a fluorescent dye is linked to an antibody for diagnostic purposes

Question 12

Enzyme linked immunosorbent assay (ELISA)

Answer 12

is used to test for HIV; can test 94 separate human serums for HIV in the wells at once; the bottom of the well has HIV virus in it, and antibodies will bind to this HIV if the test is positive; if positive the diagnosis of HIV must then be confirmed by the Western blotting test.