Chapter 17 Flashcards

1
Q

Define Antibody

A

the proteinaceous substance made by specialized lymphocytes in response to antigen

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2
Q

Define Antigen

A

Organisms of substances that provoke immune system to produce antibodies or cell mediated immunity

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3
Q

What are two examples of naturally acquired immunity?

A

active immunity and passive immunity

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4
Q

What is an example of an artificially acquired immunity?

A

a vaccine

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5
Q

What is an example of a serum protein?

A

Gamma Globulin

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6
Q

What does the humoral immune system produce?

A

antibodies

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7
Q

What is the name for the Y shaped defensive protein?

A

antibody

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8
Q

One peptoglycan can contain more than ___ antigen.

A

one

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9
Q

There are __ different antigenic determinants on one ________.

A

5, protein

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10
Q

What are the 5 Immunoglobulin classes?

A

IgG, IgM, IgA, IgD, IgE

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11
Q

What is the function of IgG?

A

neutralization of organisms and toxins

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12
Q

What is the function of IgD?

A

regulatory role

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13
Q

What is the function of IgE?

A

monometer (allergic reactions)

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14
Q

What is the function of IgA?

A

protects murosal surface, respiratory, urogenital, intestinal, conjuction

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15
Q

What is the function of IgM?

A

used for diagnosis in aggluntination reactions.

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16
Q

The body produces antibodies ____ days after exposure.

A

4-5

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17
Q

What produces all WBC’s?

A

The mother stem cell.

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18
Q

What are some of the T cell dependent antigens?

A

bacteria, foreign RBC’s, proteins

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19
Q

What does agglutination do?

A

reduces number of infectious units to be dealt with.

20
Q

Differentiate between B and T cells.

A

B cells are humoral and cell mediated. T cells are made in the thymus.

21
Q

What do T Lymphocytes kill?

A

abnormal cells that show the flag because they’re abnormal

22
Q

What might elevated Eusinophils indicate?

A

parasite infection or allergic reaction

23
Q

Define self tolerance.

A

differentiation between self and nonself.

24
Q

What are the 6 things that antigen-antibody binding and results lead to?

A
  1. Agglutination
  2. Opsonization
  3. Activation of complement
  4. Enhanced inflammation
  5. Antibody mediation
  6. Neutralization
25
Agglutination
easy phagocytosis and antigen destroyed
26
Opsonization
leads to enhanced phagocytosis and antigen destruction
27
Activation of complement
leads to Cytolysis
28
Enhanced inflammation
antigen destruction
29
Antibody mediated
cell mediated cytotoxicity; destruction of cells and large parasites by non specific immune system.
30
Neutralization
Neutralization of bacteria, protozoa, viruses, and toxins
31
Define Cytolysis
the destruction of a cell
32
What 3 things is the monoclonal antibody used for?
1. Diagnostic use 2. Cancer treatment 3. Recombinant monoclonal
33
What is cell mediated immunity?
immunity resulting from a cell-mediated immune response; cellular immunity
34
What are the 4 types of T cells?
1. Helper (TH) cells 2. Delayed hypersensitivity T (TD) cells 3. Suppressor TR (T3) cells 4. Cytotoxic T (TC) Cells**
35
The Helper (TH) cell helps ___________.
The B Lymphocyte
36
The Delayed hypersensitivity T (TD) cells produce what?
chemical hormones that boost immune system.
37
The Suppressor TR (T3) cells program ____________.
plasma cells to die.
38
What do the Cytotoxic T (TC) cells do?
attach to cells hiding inside and kill them.
39
What is herd immunity?
When they vaccinate 95% of the herd so that if the other 5% gets infected it can't cause all of the herd to be infected.
40
What are the two examples of Toxoid vaccines?
Diphtheria, Tetanus
41
What are examples of inactivated vaccines?
Rabies, polio, influenza, salmonella typhi
42
What are the examples of live (attenuated) vaccines?
yellow fever, measles, mumps, rubella
43
What is an example of a subunit vaccine?
Recombinent DNA, Hep B
44
What are the limitations of the subunit vaccine?
protozoa and parasites, giardia, trypanosomes, AIDS virus
45
What is the conjugated vaccine?
polysaccharide + protein toxins (stronger together)
46
What is the nucleic acid vaccine for?
viruses; highly mutating organisms such as cancer, HIV, influenza