Chapter 2 - Emergencies Flashcards
Areas involved by angioedema
Reticular dermis, SQ, submucosal layers of non-dependent areas
Non-pitting, non-pruritic, 24-96 hr (acute if <6 wk)
Tests for hereditary angioedema
We C1 esterase inhibitor
C4
Recurrent angioedema also caused by ACEi.
How Ludwig’s angina causes airway obstruction
FOM swelling —> tongue posterior
Clinical Sign of IFS
Tissue lacks sensation
When to convert cric to trach
Within 24 hours
Bacteria causing Epiglottitis
H Flu, S Pyogenes (GABHS), S Pneumo, S Aureus
Signs of epiglottitis
Kid: dyspnea, drool, stridor, fever
Adult: severe sore throat, odynophagia, hoarseness
Tripod!
Diagnosis and Management of Epiglottitis
Lateral XR thumb print
Kids: DL in OR
Adults: may do fiberoptic nasal if stable
Intubate if distress, ICU observe if not
2/3 Ceph, humidified air, IV steroid, racemic epi
Causes and Workup of Angioedema
Medication, foods, infxn, insect, latex, radiology contrast
Ask about laryngeal involvement (hoarse, voice change, odynophagia, stridor). May do Laryngoscopy. ICU if laryngeal involvement
Treatment of angioedema
- H1 and H2 anti-histamine
- Steroids (if anaphylaxis, laryngeal edema, severe and unresponsive to anti-H
- Epinephrine maybe
For Hereditary: Danazol prophy, FFP acutely
MOE: Mortality, Bacteria
50-80% (near 100% if CN abnl, usually VII)
Pseudo (mucoid coat deters phagocytosis, neurotoxin)
If Ca/HIV: asperg, S Aureus, Proteus, Klebsiella, Candida
Diagnosis of MOE
CT Temp (bone destruction) Need 30-50% destroyed to show on CT If NL but high suspicion: Bone scan or gallinium scintigraphy
Treatment of MOE
Fluoroquin + Aminoglyc
Aural toilet, debride granulation tissue
HBO
IFS Bacteria
Asperg
Zygomycetes (Rhizopus, Mucor, Rhizomucor)
Function as saprophytes in environment - pathologic in immunocomp host
IFS Mortality and Tx
20-80%, worse if old, heme Ca, Brain/Eye involve
Culture-dir anti-fungal, debride, underlying dz