Chapter 19: Oncology Flashcards
aden/o
Gland
angi/o
Vessel
cancer/o
Crab, cancer
capsul/o
A little box
carcin/o
cancer
chondr/o
Cartilage
chori/o
Chorion
cyt/o
Cell
dendr/o
Tree
duct/o
To lead
fibr/o
Fiber
filtrat/o
To strain through
gli/o
Glue
hem/o
Blood
immun/o
Safe, immunity
lei/o
Smooth
malign/o
Bad kind
medull/o
Marrow
melan/o
Black
mening/i
Meninges, membrane
myc/o
Fungus
myel/o
Bone marrow
nephr/o
Kidney
neuro/o
Nerve
Cancer
CA; a latin word meaning crab
cancer
refers to any malignant tumor, neoplasm, or oncoma.
surgical techniques
are being used to remove cancerous tissue, and it is usually possible to excise all the cancer cells when the malignancy is found at its earliest stages.
Two principal means of treatment for patients with cancer
chemotherapy and radiation therapy
60% of cancers
occur in people over age 65
anatomical site
indicates where the cancer originated in the body.
carcinomas
make up the great majority of all cancers and are malignant tumors of epithelial tissues: found in the breast, stomach, uterus, tongue, and skin
squamous carcinoma
cancer of squamous epithelium
basil cell carcinoma
type of skin cancer
bronchogenic carcinoma
cancer originating in the bronchus of the respiratory tract
sarcomas
originate in connective or supportive tissues of the body such as the muscles, tendon, fat , joins, and bone
osteosarcoma
cancer of the bone
leukemias
cancers of the blood-forming tissues
lymphomas
cancerous tumors of the lymph nodes
myelomas
are cancerous tumors arising in the hemopoietic portion of the bone marrow
differentiation
normal cell development, immature cells undergo normal changes as they mature and assume their specialized functions
dedifferentiation
the failure of immature cells to develop specialized functions
malignant cells
usually multiply rapidly, forming a mass of abnormal cells that enlarges, ulcerates, and sheds malignant cells that invade surrounding tissues.
based on microscopic analysis, malignant tumors are classified into grades
I, II, III, IV This system is used to report the prognosis of the disease and to determine if the tumor is likely to respond to radiation or chemotherapy, as well as the prognosis for surgery
grade I
least malignant tumors. Only a few cells are undergoing mitosis, however, some abnormality does exist
grade II
moderately undifferentiated. More cells are undergoing mitosis and the pattern is fairly irregular
grade III
many undifferentiated cells. Tissues origin can be difficult to recognize. Many cells undergoing mitosis
grade IV
the least differentiated and high degree of malignancy
Two ways in which malignant cells spread to body parts
invasive growth and metastasis
invasive growth
spreading process of a malignant tumor into adjacent normal tissue
active migration
the malignant cells break away from the neoplasm (new growth), invade surrounding tissue, divide, form secondary neoplasms, and then reunite with the primary tumor as growth continues
direct extension
multiplication of malignant cell is rapid and subsequently spread into surrounding tissues via the interstitial spaces accompanied by engulfment and destruction of normal cells. ex. breast cancer can spread to the bone, lung, or liver
metastasis
the process by whereby cancer cells are spread from a primary site to distant secondary sites elsewhere in the body. This usually occurs when malignant cells invade the bloodstream or lymph system and are transported to a secondary site where they become lodged and form a neoplasm
staging
uses letters T=tumor N=node M=metastasis to indicate the spread and uses numerical subscripts to indicate degree of tumor involvement
T2N1M0
Indicates, primary tumor is at stage II, abnormality of regional lymph nodes at stage I, and no evidence of distant metastasis
A numerical system is also used to classify the staging of cancer
Stage 0: treatable, cancer in situ(limited to the inner lining surface of the organ and not invading the organ)
Stage I
Cancer limited to the tissue of origin and has not spread past the tissue or organ where it started
Stage II
Limited local spread of cancerous cells, sometimes to lymph nodes
Stage III
Extensive local and regional spread of cancer, usually to draining lymph nodes
Stage IV
Distant metastasis, has spread beyond the regional lymph nodes to distant parts of the body
The American Cancer Society has 7 warning signals of cancer that spell CAUTION
C: change in bowel habits, A: a sore that does not heal, U: unusual bleeding or discharge, T: thickening or lump in breast or elsewhere, I: indigestion or difficulty in swallowing, O: obvious change in wart or mole, N: nagging cough or hoarseness
An annual physical examination
could be the best means to protect a person’s state of health
Visualization by Endoscopy
provides the physician a direct view of certain portions of the body
sigmoidoscopy
use of a sigmoidoscope to examine the lower 10 inches of the large intestines
laryngoscopy
use of a laryngoscope to examine the interior of the larynx
bronchoscopy
use of a bronchoscope to examine the bronchi
gastroscopy
use of a gastroscope to examine the interior of the stomach
cystoscopy
use of a cystoscope to examine the bladder
colposcopy
use of a colposcope to examine the cervix and vagina
proctoscopy
use of a proctoscope to examine the anus and rectum
colonoscopy
use of a colonoscope to examine the colon
laparoscopy
use of a laparoscope to examine the abdomen
Laboratory Analysis
plays a key role in detecting specific types of cancer
pap smear test
cytological screening test developed by Dr. George Papanicolaou and used to detect the presence of abnormal or cancerous cells from the cervix and vagina
fecal occult blood test
test to detect occult (hidden) blood in the stool (feces) if present, further testing would be needed to check for possible cancer of the colon
sputum cytology test
microscopic examination of sputum to detect abnormal or cancerous cells of the bronchi and lungs
blood serum test
analysis of blood serum to obtain useful information about certain proteins synthesized by cancer. two tests are AFP and HCG
Alpha-fetoprotein test (AFP)
test to diagnose or monitor fetal distress or fetal abnormalities, diagnose some liver disorders, and screen for and monitor some cancers; higher than normal levels and indicate cancer in testes, ovaries, biliary tract, stomach, or pancreas