Chapter 18 Flashcards
on by default; binding of repressor shuts off transcription
Repressible operon
off by default; binding of repressor turns on transcription
Inducible operon
How does the lac operon work?
When the lac operon binds onto the repressor, this allows transcription of enzymes to happen
How does the trp operon work?
When the repressor binds to the operator, it prevents enzyme production by blocking RNA polymerase from doing transcription
Sequence of nucleotides near the start of an operon to which an active repressor can attach
Operator
Protein that inhibits transcription
Repressor
Any substance that slows down or stops an enzyme catalysed reaction
Inhibitor
Consists of a promoter, operator, cluster of genes
Operon
A gene that is involved in the production of a substance that controls or regulates the expression of one or more genes
Regulatory Gene
a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid
Missense mutation
is a point mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed mRNA, and in a truncated, incomplete, and usually nonfunctional protein product.
Nonsense mutation
Why do nosense mutation cause a total lack of pain sensation?
A stop codon is produced, the protein product would be non-functional
Why do missense mutations cause multiple pain disorders?
They can code for different amino acids, causing pain sensations to vary