Chapter 16 P2 Flashcards
What action does growth hormone have on metabolism?
Increases blood levels of fatty acids and glucose by glycogen breakdown (anti-insulin effect).
What indirect actions does growth hormone have on growth?
Mediates growth via growth-promoting proteins –
insulin-like growth factors (IGFs).
What do IGFs stimulate?
Increased protein synthesis; cell growth and proliferation.
Formation of collagen and deposition of bone matrix.
What are the major targets for growth hormone?
bone and skeletal muscle.
What regulates GH release?
Hypothalamus hormones
What hormones stimulates release of GH?
Growth hormone–releasing hormone
GHRH
What hormone inhibits release of growth hormone?
Growth hormone–inhibiting hormone
GHIH) (somatostatin
What hunger hormones stimulates release of GH?
Ghrelin
What does hypersecretion of GH cause in adults and in children?
Gigantism in children
Acromegaly in adults
What does hyposecretion of growth hormone cause in children?
Pituitary dwarfism
What does thyrotropin do?
Stimulates normal development and secretory activity of thyroid.
What hormones triggers the release of Thyrotropin?
Thyrotropin releasing hormone from hypothalamus
What is TSH inhibited by?
Rising blood levels of thyroid hormones that act on pituitary and hypothalamus
What does corticotropin do?
Stimulates adrenal cortex to release
corticosteroids.
What triggers the release of ACTH (what hormone)?
Hypothalamic corticotropin-releasing hormone
What external and internal factors alters release of ACTH?
Fever
Hypoglycemia
Stressors
What are the two gonadotropins?
FSH
LH
What does FSH do?
Stimulates gamete production
What does LH do?
Promotes production of gonadal hormones
When are gonadotropins seen in the blood?
After puberty hits
What triggers release of Gonadotropins?
Gonadotropin-releasing hormone during and after puberty
What suppresses gonadotropins?
Gonadal hormones (feedback inhibition)
What does prolactin do?
Stimulates milk production