Chapter 16- Development, Cancer, And Stem Cells Flashcards
Differentiation
The process in which cells become specialized in structure and function
Model organism
Species that are easy to raise in a lab such as a fruit fly
Morphogenesis
Development of the form of an organism and its structure
Cytoplasmic determinants
Maternal substances in the egg that influence the course of early devolpment
Induction
A process where a embryonic cell signals another embryonic cell via cell surfaced receptors
Determination
The unseen event that leads to the observable differentiation of a cell
Apoptosis
Programmed cell death
Pattern formation
The development of a spatial organization in which the tissues and organs of an organism are in their characteristic places
Positional information
The molecular cues that control pattern formation are
Homeotic genes
Control pattern formation in the late embryo larva and adult
Embryonic lethals
Mutations with phenotypical changes that cause death in the embryo stage or the larva stage
Maternal Effect Gene
Genes determined by the mother that control the cytoplasmic determinants, and when mutant in mother always cause dead babies
Egg polarity genes
Like maternal effect genes but these control the position of the axis, also mutant cause dead babies
Bicoid
A gene that determines where the front half of the body will be and if absent the babies will have two butts
Morphogens
Substance that cause mutations in the LOOK UO DEF.
Totipotent
A cell with the potential to dedifferentiate and give rise to all specialized cells in organism
Stem Cell
Is a relatively unspecialized cell that can reproduce itself indefinitely under special conditions and give rise to all specialized cells of organism
Pluripotent
Able to turn into all specialized cell types
Oncogenes
Cancer causing genes found in some viruses
Proto-oncogenes
Code for proteins that cause late normal cell growth and division, found in organisms’ genome
Tumor-suppressor genes
Encode for proteins that protect against uncontrolled cell growth
Ras gene
Encodes the ras protein which is a G protein and relays a signal from a growth factor receptor and to protein kinases
P53 gene
Is a tumor suppressor gene that codes for a protein that promotes synthesis of cell cycle blocking proteins