Chapter 14- Gene Expression Flashcards

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0
Q

Transcription

A

Synthesis of RNA using information in the DNA

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1
Q

Gene Express

A

The process in which DNA directs the synthesis of proteins

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2
Q

mRNA

A

Strand of RNA that carries genetic message from DNA to protein synthesizing part of cell

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3
Q

Translation

A

Synthesis of a polypeptide using the information in mRNA

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4
Q

Ribosome

A

Complex of particles that facilitate the orderly linking of amino acids to polypeptide chains

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5
Q

Primary Transcipt

A

The initial part of RNA that is not translated into a protein

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6
Q

Triplet Code

A

Genetic instruction for a polypeptide chai written in three nucleotide words

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7
Q

Template strands

A

Provides pattern or template for the sequence of nucleotides in a RNA transcript

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8
Q

Codon

A

mRNA nucleotide triplet

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9
Q

Reading frame

A

The triplet grouping of ribonucleotides used by translation machinery

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10
Q

RNA polymerase

A

Pries apart the stand of DNA and makes RNA form free floating nucleotides, complementary to DNA

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11
Q

Promoter

A

DNA sequence where RNA polymerase attaches and begins its thing

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12
Q

Terminator

A

The part of RNA that ends the transcription

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13
Q

Transcription unit

A

Stretch of DNA that is transcribed into a RNA molecule

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14
Q

Transcription factors

A

Collection of proteins that mediate the binding of RNA polymerase and initiation of transcription

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15
Q

Transcription initiation complex

A

Complex of RNA polymerase and transcription factors bound the promoter

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16
Q

TATA box

A

In forming the initiation at complex at a eukaryotic promoter

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17
Q

Poly-A tail

A

At the 3’ end, an enzyme adds 50-250 adds adenine nucleotides

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18
Q

RNA processing

A

Both ends of primary transcripts are altered by enzymes in Eukaryotes before the genetic messages are dispatch to the cytoplasm

19
Q

5’ cap

A

A modified form of guanine nucleotide added I tot the 5’ end after transcription of first 20-49 nucleotides

20
Q

RNA splicing

A

A cut and paste job of a large removal of RNA molecules that is originally synthesized

21
Q

Introns

A

The noncoding segments of nucleic acid that lies between coding regions

22
Q

Exons

A

The coding regions of the DNA that is expressed

23
Q

Alternative RNA Splicing

A

Genes that give rise to two or more different polypeptide depending on which segments are treated as exons during RNA processing

24
Q

Spliceosome

A

A large complex of proteins and small RNA that remove introns

25
Q

Ribozymes

A

RNA molecules that function as enzymes

26
Q

tRNA

A

The function of tRNA is to transfer amino acids from the cytoplasmic pool of amino acids

27
Q

Anticodon

A

The particular nucleotide triplet that base pairs to a specific mRNA codon

28
Q

Aminoacyl-tRNA synthetases

A

The correct matching up if tRNA and amino acids is carried out ha family of related enzymes

29
Q

Wobble

A

Flexible base pairing at the 5’ end of tRNA anticodon can pair with either a or g at the Thrid position

30
Q

rRNA

A

What the anti codons are made out of

31
Q

P site

A

Where the amino acid binds to polypeptide

32
Q

A site

A

Point where the tRNA is added

33
Q

E site

A

Exit site

34
Q

Signal peptide

A

The polypeptides of proteins that are destined for the endomembrane

35
Q

Signal recognition particle

A

Functions as an escort that brings ribosome to receptor in er membrane

36
Q

Point mutations

A

Change in a single nucleotide pair of gene

37
Q

Nucleotide pair substitution

A

Replacement of one nucleotide and its partner

38
Q

Silent mutations

A

No effect on the phenotype

39
Q

Missesne mutations

A

Change one amino acid to another and have little effects on the protein

40
Q

Nonsense mutations

A

Causes translations to be canceled and stops the polypeptide and make the

41
Q

Insertions

A

Addition of nucleotide

42
Q

Deletion

A

Loss of nucleotide

43
Q

Frame shift mutation

A

When the points where the codon are placed are moved

44
Q

Mutagen

A

Interact with DNA and cause mutations