Chapter 14 and 15 ADRENERGIC AGONISTS AND CHOLINERGIC ANTAGONISTS Flashcards
What are the two classifications of adrenergic agonists **
Catecholamines
Noncatecholamines
Can Catecholamines be taken PO why or why not**
No they can not be taken PO because enzymes in the stomach will degrade them before they can reach the bloodstream
Can non catecholamines be taken PO **
Yes they are not broken down in the stomach
can catecholamines cross the blood brain barrier? *
No they can not cross the BBB
can Noncatecholamines cross the blood brain barrier? **
yes they are better able to enter the CNS
What are three common effects of alpha 1 agonists
Remember the three P’s
-Pee (urinary retention)
-Pupils (dilate)
-Peripheral vasoconstriction
what are Alpha 1 agonists prescribed for
Nasal congestion
Hypotension (Since it causes peripheral vasoconstriction)
What are Alpha 2 agonists prescribed for
Treatment of hypotension
What do Beta 1 receptors control?
Control the heart so if they are stimulated they increase heart rate
(think 1 heart=Beta 1)
What do Beta 2 receptors control
Lungs
uterus
(Think 2 lungs=Beta 2)
What is an important patient teaching when it comes to storing epinephrine**
Will break down if it is exposed to light so store in a dark place
What are some considerations when administering epinephrine**
-use cardiac monitor (since it can put strain on the heart)
-Inform prescriber of changes in in’s outs (because of retention)
-monitor for hyperglycemia (since epi causes glucose release from the liver)
-examine ocular and nasal mucosa
What are alpha 1 agonists used to treat
used to treat conditions with hypertension since it stimulates peripheral vasoconstriction
What are some contraindications of Alpha 1 agonists **
-Hyperthyroidism
-Diabetes
pre existing bradycardia
what is the prototype Alpha-1 agonist*
Phenylephrine
