Chapter 14: Amines and Amides

Question 1

Is indigo an amine?

Answer 1

yes

Question 2

Amines are derivatives of ______, NH3, in which one or more hydrogen atoms are replaced with alkyl or aromatic groups

Answer 2

Ammonia

Question 3

Amines are derivatives of ammonia, NH3, in which one or more hydrogen atoms are replaced with _____ or ____ groups

Answer 3

Alkyl(Ch3/Ch2) or aromatic(benzene)

Question 4

Amines are classified as ______, _____, and ______

Answer 4

primary, secondary or tertiary

Question 5

A _______ amine has ONE carbon group bonded to the nitrogen atom

Answer 5

primary

Question 6

A ______ amine has TWO carbon groups bonded to the nitrogen atom

Answer 6

secondary

Question 7

A ________ amine has THREE carbon groups bonded to the nitrogen atom

Answer 7

tertiary

Question 8

H-N(Ch2)-H is which classification of an amine?

Answer 8

Primary

Question 9

H-N(Ch3)-Ch3 is which classification of an amine?

Answer 9

Secondary

Question 10

Ch3-N(Ch3)-Ch3 is which classification of an amine?

Answer 10

Tertiary

Question 11

Is Methylamine primary, secondary, or tertiary?

Answer 11

Primary (methyl= Ch3)

Question 12

Is Dimethylamine primary, secondary, or tertiary?

Answer 12

Secondary (Dimethyl= ch3-ch3)

Question 13

Is Trimethylamine primary, secondary, or tertiary?

Answer 13

Tertiary (Trimethyl: ch3-ch3-ch3)

Question 14

Primary and secondary amines with fewer than ____ carbons are soluble in water

Answer 14

6

Question 15

_____ amines can form hydrogen bonds only with water molecules

Answer 15

Tertiary

Question 16

1’ and 2’ amines act as a bronsted-Lowry ______ because the lone electron pair on the nitrogen accepts the H+ from water to produce an ammonium ion and a hydroxide ion (OH-)

Answer 16

base

Question 17

An amine salt forms when: amines such as those responsible for the odor in fish are neutralized by an _____

Answer 17

acid

Question 18

Amines are usually converted to their ______ _____ before being used as drugs

Answer 18

ammonium salt

Question 19

ammonium salts are solid/liquid at room temperature, odorless/strong odor, and soluble/insoluble in water and body fluids. Choose the correct options

Answer 19

Solid
Odorless
soluble

Question 20

Ammonium salts are used as the ____ ingredients in medications

Answer 20

active

Question 21

What is the ammonium salt in Benadryl?

Answer 21

Diphenylhydramine

Question 22

______ is used as a bronchodilator in the decongestant sudafed

Answer 22

Ephedrine

Question 23

What is the ammonium salt name for cocaine?

Answer 23

Cocaine Hydrochloride

Question 24

How can cocaine hydrochloride be converted back to its free amine?

Answer 24

By treating it with a strong base (also known as crack cocaine)

Question 25

Alkaloids are physiologically active compounds produced by plants that contain _____

Answer 25

nitrogen

Question 26

What is used in anesthetics, antidepressants, stimulants, and are habit forming?

Answer 26

Alkaloids

Question 27

Is nicotine an alkaloid?

Answer 27

yes

Question 28

Nicotine is a stimulant that increases the level of _______ in the blood

Answer 28

adrenaline

Question 29

Caffeine is an ______ found in coffee, tea, chocolate, and soda, and is a stimulant of the PNS or CNS?

Answer 29

alkaloid/Central nervous system (It also has two benzene rings which explains its awesome smell)

Question 30

Morphine and codeine are ______ obtained from the oriental poppy plant

Answer 30

alkaloids

Question 31

Amides are derivatives of ______ ____ in which a nitrogen group (-NH2) replaces the hydroxyl (–OH) group of the ____ _____

Answer 31

Carboxylic acids (ex: CH3–C(O)—OH becomes CH3–C(O)–NH2

Question 32

A popular amide is __________

Answer 32

acetaminophen(tylenol)

Question 33

Amides are produces by reacting a carboxylic acid with ______, or a primary or secondary amine, and ____

Answer 33

ammonia, and heat.

Question 34

_____ is the end product of protein metabolism

Answer 34

urea

Question 35

_____ is removed from the blood by the kidneys

Answer 35

urea

Question 36

_____ is excreted in the urine

Answer 36

Urea

Question 37

Barbiturates act as _______

Answer 37

sedatives (phenobarbital and pentobarbital)