chapter 13: pet imaging of the brain

Question 1

which of the following may cause dementia?

hypothyroidism
vitamin b12 deficiency
syphilis
alcoholism
HIV
all of the above

Answer 1

all of the above

Question 2

the primary areas of the brain affected by AD are

temporal lobe
parietal lobe
frontal lobe
temporal and parietal lobes
frontal and temporal lobes

Answer 2

temporal and parietal lobes

Question 3

many patients with AD posses the genetic marker called

apoE5 allele
apoE4 allele
apoE3 allele
apoE2 allele

Answer 3

apoE4 allele

Question 4

all of the following may help scan interpretation with dementia patients except

acquiring in list mode
acquiring in frame mode
using a head holder
providing clear instructions

Answer 4

acquiring in frame mode

Question 5

T/F: white matter appears intensely hypermetabolic on fdg pet images

Answer 5

false. gray matter is intensely hypermetabolic, white matter is hypometabolic

Question 6

memory, language, and sensation are controlled by the

frontal lobe
parietal lobe
temporal lobe
brain stem
cerebellum

Answer 6

parietal lobe

Question 7

the sylvian fissure is located

between the parietal and temporal lobes

between the temporal and frontal lobe

between the parietal and occipital lobes

between the parietal and frontal lobe

Answer 7

between the temporal and frontal lobe

Question 8

memory and speech recognition are controlled by the

frontal lobe
parietal lobes
temporal lobes
occipital lobes

Answer 8

temporal lobes

Question 9

name four metabolic disorders that may cause dementia

Answer 9

alcohol induced, chronic electrolyte imbalance, vitamin b12 deficiency, HYPOthyroidism

Question 10

name three infection/inflammation processes that may cause dementia

Answer 10

syphilis, creutzfeldt-jakob disease, HIV encephalopathy

Question 11

about how many people worldwide have AD?

100 million
50 million
45 million
35 million

Answer 11

35 million

Question 12

what is the primary symptom of AD?

personality changes
loss of cognitive function
memory loss
behavioral changes

Answer 12

memory loss

Question 13

T/F: patients must fast before FDG PET imaging for dementia

Answer 13

true

Question 14

how long is the emission scan for FDG pet imaging for dementia?

10 min
15 min
20 min
30 min

Answer 14

10 min

Question 15

how does gray matter typically appear on fdg pet images of the brain?

Answer 15

intensely hypermetabolic

Question 16

the tentorium divides

Answer 16

the cerebrum and cerebellum

Question 17

what differentiates FTD from AD on fdg pet images of the brain?

Answer 17

sparing of the parietal cortex for FTD

Question 18

FTD is caused by the deposition of

beta-amyloid plaque and tau protein
tau protein only
tau protein and alpha-synuclein
alpha-synuclein only

Answer 18

tau protein only

Question 19

dementia with lewy bodies is caused by the deposition of

Answer 19

alpha-synuclein and amyloid plaque

Question 20

dementia associated with parkinson’s disease is caused by the deposition of

Answer 20

alpha - synuclein

Question 21

f18 beta-amyloid images of the brain normally show what kind of uptake?

Answer 21

higher uptake in white matter, little uptake in gray matter

Question 22

f18 florbetapir dose in MBq

Answer 22

370 MBq (10 mCi)

Question 23

f18 florbetapir localization time

Answer 23

30-50 min

Question 24

f18 flutemetamol dose in MBq

Answer 24

185 MBq (5 mCi)

Question 25

f18 flutemetamol localization time

Answer 25

90 min

Question 26

f18 florbetaben dose in MBq

Answer 26

300 MBq (8 mCi)

Question 27

f18 florbetaben localization time

Answer 27

45-130 min