Chapter 13 - Nervous System Flashcards
Neurobiology
study of nervous system (includes neuroanatomy and neurophysiology)
Nervous System Functions
- Sensory
- Perception
- Integration
- Motor Planning
Two Main Divisions of the Nervous System
- Central Nervous System (CNS) - brain and spinal cord
2. Peripheral Nervous System (PNS) - nerves and ganglia
Sensory (Afferent) Division
- from receptors to CNS
- Somatic = signals from skin, muscle, bones, and joints
- Visceral = signals from thoracic and abdominal cavities
Motor (Efferent) Division
- from CNS to glands and muscles
- Somatic = signal to skeletal muscle
- Visceral = signal to glands, cardiac and smooth muscle
- Sympathetic = arouse the body
- Parasympathetic = energy intake and conservation
Nerve Cell
neuron
Fundamental Physiological Properties of Neurons
- Excitability - can respond to stimuli
- Conductivity - can send signals to distant locations quickly
- Secretion - can release chemical messengers (neurotransmitters)
Functional Classes of Neurons
- Sensory (Afferent)
- Interneurons (Association Neurons)
- Motor (Efferent)
Sensory (Afferent) Neurons
detect stimuli
Interneurons (Association Neurons)
receive signals from other neurons and make decisions about response
Motor (Efferent) Neurons
send signals to muscles to provide response
Structure of a Neuron
- Neurosoma (soma or cell body) - control center
- Nissl Bodies - contain compartmentalized rough ER
- Dendrites - receive signals
- Axon - generates action potentials (signals)
- Synaptic Knob (terminal knob) - ending of axon branch that communicates with another cell
Multipolar Neuron
two or more dendrites, one axon (most common in brain & spinal cord)
Bipolar Neuron
one dendrite, one axon (olfactory cells, retina, & inner ear)
Unipolar Neuron
single process (to spinal cord)
Anaxonic Neuron
many dendrites, NO axon (brain, retina, & medulla)
Neuroglia
- “glial cells”
- outnumber neurons 10 to 1
- support cells (protect and aid in function)
- glia means “glue” (bind neurons together)
Types of Neuroglia
CNS: 1. Oligodendrocytes 2. Ependymal Cells 3. Microglia 4. Astrocytes PNS: 1. Schwann Cells 2. Satellite Cells
Oligodendrocytes
- neuroglia of CNS
- myelinate to assist conduction
Ependymal Cells
- neuroglia of CNS
- secrete and circulate cerebrospinal fluid
Microglia
- neuroglia of CNS
- help in defense and disposal
Astrocytes
- neuroglia of CNS
- provide support and nourishment
Schwann Cells
- neuroglia of PNS
- myelinate to assist conduction
Satellite Cells
- neuroglia of PNS
- provide electrical insulation and regulate the chemical environment of the neurons
Myelin
- analogous to insulation on a wire
- Oligodendrocytes make fatty white matter of CNS
- Internodes = fiber segments covered by myelin
- Nodes of Ranvier = fiber segments with gaps in myelin
- Neurilemma = outermost coiled layer of a Schwann Cell
Unmyelinated Nerve Fibers
unmyelinated PNS axons are surrounded by Schwann cells, but the Schwann cells do not coil densely around these axons
Signal conduction speed depends on two factors:
- diameter of fiber (larger is faster)
2. presence of myelin (myelinated is faster)
Nerve Regeneration
- if a cell body remains intact, cut nerve fibers can regenerate
- Schwann cells secrete nerve growth factors
- Schwann cells and endoneurium produce regeneration tube to direct regrowth
- CNS neurons cannot regenerate
Synapses
- meeting point of neuron and other cell
- presynaptic neuron to postsynaptic neuron
- chemical or electrical
Chemical Synapses
presynaptic neuron releases neurotransmitter to postsynaptic cell
Neurotransmitters
- messenger molecules
- some are excitatory, some are inhibitory
- Acetylcholine (NMJ)
- Norepinephrine (sympathetic)
- Glutamine & Aspartate (excitatory)
- GABA & Glycine (inhibitory)
- Dopamine, Seratonin, Histamine
Structures at a Synapse
- synaptic knob of presynaptic nerve
- contains synaptic vesicles (packets of neurotransmitters)
- synaptic cleft
- neurotransmitter receptors on postsynaptic cell
Electrical Synapse
- connects neurons, neuroglia, cardiac and single unit smooth muscle cells
- adjacent cells joined by gap junctions
- ions diffuse from cell to cell
- quick transmission
- no integration or decision-making