Chapter 10 (Muscular Tissue VII) Flashcards

1
Q

Neuromuscular junction (NMJ)

A

Motor neurons have a threadlike axon that extends from the brain or spinal cord to a group of muscle fibers
Action potentials arise at the interface of the motor neuron and muscle fiber

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2
Q

Synapse

A

Where communication occurs between a somatic motor neuron and a muscle fiber

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3
Q

Synaptic cleft

A

Gap that separates the two cells

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4
Q

Neurotransmitter

A

Chemical released by the initial cell communicating with the second cell

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5
Q

Synaptic vesicles

A

Sacs suspended within the synaptic end bulb containing molecules of the neurotransmitter acetylcholine (Ach)

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6
Q

Motor end plate

A

The region of the muscle cell membrane opposite the synaptic end bulbs
Contain acetylcholine receptors

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7
Q

Nerve impulses elicit a muscle action potential:

A

Release of acetylcholine
Activation of ACh receptors
Production of muscle action potential
Termination of ACh activity

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8
Q

Release of acetylcholine

A

Nerve impulse arriving at the synaptic end bulbs causes many synaptic vesicles to release ACh into the synaptic cleft

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9
Q

Activation of ACh receptors

A

Binding of ACh to the receptor on the motor end plate opens an ion channel
Allows flow of Na+ to the inside of the muscle cell

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10
Q

Production of muscle action potential

A

The inflow of Na+ makes the inside of the muscle fiber more positively charged triggering a muscle action potential
The muscle action potential then propagates to the SR to release its stored Ca++

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11
Q

Termination of ACh activity

A

Ach effects last only briefly because it is rapidly broken down by acetylcholinesterase (AChE)

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