Chapter 10 - Muscle Tissue & Physiology Flashcards

1
Q

Six functions of skeletal muscle

A

Produce skeletal movement, maintain posture and position, support soft tissues, guard entrances and exits, maintain body temperature, and store nutrients

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2
Q

Skeletal muscle

A

Organs composed mainly of skeletal muscle tissue also containing connective tissues, nerves, and blood vessels

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3
Q

Muscle fiber

A

Cell in skeletal muscle tissue

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4
Q

Intercalated discs

A

Regions where adjacent cardiocytes interlock and where gap junctions permit electrical couping between the cells

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5
Q

Gap junctions

A

Connections between cells that permit electrical coupling

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6
Q

Sarcolemma

A

Plasma membrane of a muscle fiber

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7
Q

Sarcoplasm

A

Cytoplasm of the muscle fiber

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8
Q

Transverse tubules

A

T tubules, narrow tubes whose surfaces are continuous with the sarcolemma and extend deep into the sarcoplasm, conducting electrical impulses throughout the cell interior

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9
Q

Myofibrils

A

Cylindrical structures, the active shortening of which is responsible for skeletal muscle fiber contractions

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10
Q

Myofilament

A

Protein filaments arranged into bundles that make up myofibrils

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11
Q

Thin filament

A

A cytoskeletal filament in a skeletal or cardiac muscle cell; consists of actin, troponin, nebulin, and tropomyosin

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12
Q

Actin

A

The protein component of microfilaments that forms thin filaments in skeletal muscles and produces contractions of all muscles through interaction with thick filaments (myosin)

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13
Q

Thick filament

A

A cytoskeletal filament in a skeletal or cardiac muscle cell; composed of myosin, with a core of titin

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14
Q

Myosin

A

Ptrotein component of thick filaments

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15
Q

Triad

A

Combination of a pair of terminal cisternae plus a T tubule

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16
Q

Sarcoplasmic reticulum

A

Membrane complex that forms a tubular network around each individual myofibril, stores calcium

17
Q

Terminal cisternae

A

Expanded chambers where tubules of the SR elarge and fuse on either side of a T tubule

18
Q

I band

A

Light band of the sarcomere, primarily thin filaments

19
Q

A band

A

Dark band of the sarcomere, containing overlapping thick and thin filaments with thick filaments at the center of each sarcomere

20
Q

Z lines

A

Bisect the I bands and mark the boundary between adjacent sarcomeres

21
Q

M line

A

Center of the A band, center of the sarcomere

22
Q

Sarcomere

A

Smallest functional unit of muscle fiber

23
Q

Active site

A

Location on actic where myosin can bind to produce muscle contraction

24
Q

Troponin

A

Molecule consisting of three globular subunits - when Ca2+ binds to troponin, it causes the tropomysin to change shape, exposing the active site and allowing muscle contraction

25
Tropomyosin
Covers active sites and prevents actin-myosin interaction; moved by troponin
26
Cross-bridge
When myosin heads interact with thin filaments during a contraction
27
Sliding filament theory
Where thin filaments are sliding toward the center of each sarcomere alongside the thick filaments
28
Polarized
Unequal charge distribution, with the sarcoplasm having a negative charge and the outer surface having apositive
29
Depolarization
A change in membrane potential from a negative value toward 0 mV
30
Repolarization
The movement of the membrane potential away from a postitive value and toward the resting potential
31
Hyperpolarization
Result of movenemt of potassium ions out of a cell; membrane potential becomes more negative
32
Neuromuscular junction
Synapse between two skeletal muscle fibers
33
Synapse
Location where communication between aneuron and another cell occurs
34
Axon terminal
Synaptic terminal of a neuron, the cytoplasm of which contains vesicles filled with acetylcholine (AC h), a neurotransmitter
35
Motor end plate
Specialized region of the sarcolemma which receives communication from axon terminal
36
Synaptic cleft
Narrow space between axon terminal and motor end plate
37
Excitation-contraction coupling
Link between the generation of an action potential in the sarcolemma and the start of a muscle contraction