Chap 37 (exam 4) Flashcards

1
Q
The nurse is teaching a group of patients about the use of bronchodilators. It is important to remind them that using bronchodilators too frequently may cause which adverse effects? Select all that apply
Blurred vision
Increased heart rate
Decreased heart rate
Nausea
Nervousness
Tremors
A

Increased heart rate
Nausea
Nervousness
Tremors

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2
Q

For patients taking a leukotriene receptor antagonist, the nurse should include which information in the patient teaching?
If a dose is missed, the patient may take a double dose to maintain blood levels
The patient should gargle or rinse the mouth after using the inhaler
The medication should be taken at the first sign of bronchospasm
Improvement should be seen within a week of use

A

Improvement should be seen within a week of use

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3
Q
Which drug acts by blocking leukotrienes, thus reducing inflammation in the lungs?
Cromolyn (Intal)
Montelukast (Singulair)
Theophylline (Elixophyllin)
Albuterol (Proventil)
A

Montelukast (Singulair)

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4
Q
A patient is experiencing status asthmaticus. The nurse will prepare to administer which drug first?
Epinephrine
Methylprednisolone (Solu-Medrol)
Cromolyn (Intal)
Montelukast (Singulair)
A

Epinephrine

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5
Q
When a patient is taking parenteral xanthine derivatives such as aminophylline, the nurse should monitor for which adverse effect?
Decreased respirations
Hypotension
Tachycardia
Hypoglycemia
A

Tachycardia

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6
Q
A patient who has asthma may be prescribed which type of inhaled drug for its antiinflammatory effects?
Corticosteroid
Anticholinergic
Xanthine derivative
Beta adrenergic
A

Corticosteroid

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7
Q
A patient is to receive a new prescription for an ipratropium (Atrovent) inhaler. The nurse will assess for which potential contraindications? Select all that apply
Allergy to soy lecithin
Allergy to peanuts
Allergy to iodine products
Hypertension
Seizure disorders
A

Allergy to soy lecithin

Allergy to peanuts

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8
Q

Tom, a 70 year old retiree who smoked for 40 years, has been diagnosed with chronic obstructive pulmonary disease (COPD); the treatment regimen prescribed includes theophylline (Theo-Dur). After a few weeks, Tom tells the nurse that he is experiencing nausea and “bad heartburn at night.” The laboratory studies show the level of theophylline in his blood to be 30 mcg/mL. What might be wrong with Tom, and how can it be corrected?

A

Tom is exhibiting some side effects of theophylline therapy, and the level in his blood is too high (the common therapeutic range for theophylline is a blood level of 10-20 mcg/dL). It is likely that the dosage will be decreased.

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9
Q

Sylvia has come to the clinic today complaining of nausea, palpitations and anxiety. She says that her heart fee’s :as if it’s going to fly out of my chest.” Physical examination confirms an increased heart rate. Sylvia’s records indicate that she as asthma for which she uses an albuterol inhaler. When asked about the inhaler, she states that she uses it “when ever I feel short of breath.” What is causing Sylvia’s complaints?

A

Sylvia is exhibiting dose-related adverse effects of the albuterol. If Sylvia is now using the albuterol more frequently as a rescue inhaler, the health care provider will need to review and adjust her medication regimen

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10
Q

Mrs. V., a 65-year-old office manager, has arthritis, glaucoma, and emphysema. The health care provider is planning treatment for her emphysema.
What 3 types of drugs might be considered for treatment of COPD?
What factor must the provider keep in mind when determining the best drug for Mrs. V.?

A

Anticholinergics, corticosteroids, beta agonists

Of concern is Mrs. V’s glaucoma. Anticholinergics are to be used cautiously in patients with acute narrow angle glaucoma

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11
Q

Several months ago, the physician prescribed an orally administered corticosteroid for Mr. Z., who has chronic bronchial asthma.
What are the disadvantages of administering the corticosteroids orally? Is there an alternative route?
Today the physician adds beclomethasone dipropoinate (Beclovent) to Mr. Z’s drug regimen and also reduces the dosage of the oral corticosteroid. Why was the oral corticosteroid not discontinued.

A

The disadvantage of administering the corticosteroids orally is that they can then lead to systemic effects, such as increased susceptibility to infection, fluid and electrolyte disturbances, endocrine effects, dermatologic effects, and nervous system effects. They can interact with other systemically administered drugs. The advantage of administering corticosteroids by inhalation is that they are delivered directly to the site of action- the lungs. This generally limits, but does not completely prevent, systemic effects.
The use of an inhaled corticosteroid frequently allows for a reduction in the daily dose of the systemic corticosteroid. This reduction should be gradual to prevent Addisonian crisis due to suppression of the adrenal gland.

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12
Q

Alice has been treated for asthma for several months and has the following inhalers: albuterol (Proventil) and fluticasone (Flovent). Which one should she choose if she experiences an asthma attack? Explain your answer

A

The albuterol is a beta agonist that can be used to treat acute bronchospasms. The fluticasone is a corticosteroid and is not effective for acute bronchospasm. Fluticasone us useful for long-term management of asthma and works to reduce inflammation

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13
Q

Justin calls the nurse at the office because he experiences “palpitations and a racing heart” every morning after breakfast. He is taking theophylline (Theo-Dur) as part of his treatment for asthma. Upon questioning, he states that he has been drinking an extra cup of coffee in the morning “to get going” because his coughing has kept him from sleeping well. What could be his problem?

A

He needs to be reminded to avoid foods and beverages that contain caffeine (e.g., chocolate, coffee, cola, cocoa, tea) because their consumption can exacerbate CNS stimulation

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14
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
How does this medication differ from corticosteroids that are used to reduce inflammation?

A

Montelukast, a leukotriene receptor antagonist, works to reduce the inflammatory response in the lungs but does not have the adverse effects that corticosteroids have

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15
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
Jennie says, “I hope this medicine works better than the other one I took when I has an asthma attack.” How will you reply?

A

Leukotriene receptor antagonists are primarily used for prophylaxis and chronic management of asthma and are not appropriate for treatment of acute asthma attacks; however, they should decrease the frequency of the attacks

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16
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
Jennie takes ibuprofen (Advil) on occasion for arthritic pain. How do you advise Jennie regarding taking over the counter drugs with montelukast?

A

You should tell Jennie that she needs to check with her health care provider before taking any over the counter medications

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17
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
After 3 months, Jennie stops taking the montelukast. She says, “my symptoms are better, and I don’t want to take medicine unless I need it.” Is this appropriate?

A

These drugs should be taken every night on a continuous schedule, even if symptoms improve

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18
Q

A patient who has a history of asthma is experiencing an acute episode of shortness of breath and needs to take a medication for immediate relief. The nurse will choose which medication that is appropriate for this situation?
A beta agonist, such as albuterol
A leukotriene receptor antagonist, such as montelukast
A corticosteroid, such as fluticasone
An anticholinergic, such as ipratropium

A

A beta agonist, such as albuterol

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19
Q

After a nebulizer treatment with the beta agonist albuterol, the patient complains of feeling a little “shaky”, with slight tremors of the hands. The patient’s heart rate is 98 beats/min, increased from the pretreatment rate of 88 beats/min. The nurse knows that this reaction is an:
Expected adverse effect of the medication
Allergic reaction to the medication
Indication that he has received an overdose of the medication
Idiosyncratic reaction to the medication

A

Expected adverse effect of the medication

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20
Q
A patient has been receiving an aminophylline (xanthine derivative) infusion for 24 hours. The nurse will assess for which adverse effect when assessing the patient during the infusion?
CNS depression
Sinus tachycardia
Increased appetite
Temporary urinary retention
A

Sinus tachycardia

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21
Q
During a teaching session for a patient who will be receiving a new prescription for the LTRA montelukast (Singulair), the nurse will tell the patient that the drug has which therapeutic effect?
Improves the respiratory drive
Loosens and removes thickened secretions
Reduces inflammation in the airway
Stimulates immediate a bronchdilation
A

Reduces inflammation in the airway

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22
Q

After the patient takes a dose of an inhaled corticosteroid, such as fluticasone (Flovent), what is the most important action the patient needs to do next?
Hold the breath for 60 seconds
Rinse out the mouth with water
Follow the corticosteroid with a bronchodilator inhaler, if ordered
Repeat the dose in 15 minutes if the patient feels short of breath

A

Rinse out the mouth with water

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23
Q

The nurse is teaching a patient about the inhaler Advair (salmeterol/ fluticasone). Which statements by the patient indicate a correct understanding of this medication? Select all that apply:
“I will rinse my mouth with water after each dose”
“I need to use this inhaler whenever I feel short of breath, but not less than 4 hours between doses”
“This medication is taken twice a day, every 12 hours”
“I can take this inhaler if I get short of breath while exercising”
“I will call my doctor if I notice white patches inside my mouth”

A

“I will rinse my mouth with water after each dose”
“This medication is taken twice a day, every 12 hours”
“I will call my doctor if I notice white patches inside my mouth”

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24
Q

what are the classes of bronchodilators

A

Beta adrenergic adonists
anticholinergic
xanthine derivatives

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25
albuterol
Ventolin, Proventil SABA beta2 specific bronchodilating beta agonist Dose-related effects (beta1 stimulated): nausea, increased anxiety, palpitations, tremors, increased heart rate
26
levalbuterol
Xopenox SABA For pts w/ tachycardia
27
Formoterol
Foradil, Perforomist | LABA
28
Salmetrol
Serevant LABA Never for acute treatment Used w/ inhaled corticosteroid twice daily Adverse effects: immediate hypersensitivity reactions, headache, HTN, neuromuscular & skeletal pain
29
Beta adrenergic agonist indications
prevention or relief of bronchospasm related to bronchial asthma, bronchitis, other pulmonary diseases
30
Beta adrenergic agonist contraindications
Drug allergy uncontrolled HTN or cardiac dysrhythmias high risk of stroke
31
Beta adrenergic agonist adverse effects
alpha/ beta agonists combos produce most: insomnia, restlessness, anorexia, cardiac stimulation, hyperglycemia, tremor, vascular headache beta2 drugs: HTN, hypotension, vascular headaches, tremor
32
Beta adrenergic agonist interaction
Nonselective beta blockers w/ beta agonist bronchodilator: beta agonist bronchodilation diminishes Beta agonists w/ MAOIs: enhanced risk of HTN Pts w/ diabetes need lower hypoglycemic drugs due to increased blood glucose may occur
33
ipratropium
Atrovent | Anticholinergic bronchodilator
34
tiotropium
Spiriva | Anticholinergic bronchodilator
35
Anticholinergic bronchodilator contraindications
drug allergy Allergy to atropine or soy lecithin Allergy to peanuts, peanut oils, soybeans, other legumes
36
Anticholinergic bronchodilator adverse effects
``` dry mouth or throat nasal congestion heart palpitations GI distress Urinary retention Increased intraocular pressure headache coughing anxiety ```
37
Xanthine derivatives
Theophylline (metabolized to caffeine in body) Caffeine Aminophylline (metabolized to theophylline in body)
38
Xanthine derivatives mechanism of action
Inhibit phosphodiesterase, which increases cAMP levels, causes bronchodilation
39
Xanthine derivatives indications
dilate airways of pts w/ asthma, chronic bronchitis, emphysema Mild to moderate causes of acute asthma Adjunct drug managing COPD
40
Xanthine derivatives contraindications
``` Drug allergy uncontrolled cardiac dysrhythmias seizure disorders hyperthyroidism peptic ulcers ```
41
Xanthine derivatives adverse effects
``` nausea vomiting anorexia gastroesophageal refluc sinus tachycardia palpitations extrasystole ventricular dysrhythmias ```
42
Theophylline
metabolized to caffeine in body | therapeutic blood level 10-20 mcg/mL
43
Leukotriene receptor antagonists
LTRAs
44
Montelukast
Singulair LTRA Bind to D4 leukotriene receptor subtype in respiratory tract tissues & organs Only oral
45
Zafirlukast
Accolate LTRA Bind to D4 leukotriene receptor subtype in respiratory tract tissues & organs Adverse effects: headache, nausea, diarrhea
46
Zileuton
``` Zyflo LTRA Indirect mechanism Inhibits enzyme 5-lipoxygenase Adverse effects: headache, nausea, dizziness, incomnia ```
47
LTRA indications
prophylaxis & long-term treatment & prevention of asthma in adults & children 12 and up Not for acute attacks Improvement in about 1 week
48
LTRA contraindications
drug allergy | allergy to povidone, lactose, titanium dioxide, cellulose derivatives,
49
Corticosteroids | Mechanism of action
Glucocorticoids | dual effect of reducing inflammation & enhancing activity of beta agonists
50
Beclomthasone diproprionate
Beclovent | Corticosteroids
51
Budesonide
Pulmicart Turbuhaler | Corticosteroids
52
Dexamethasone sodium phosphate
Decardon Phosphate Respihaler | Corticosteroids
53
Flunisolide
AeroBid | Corticosteroids
54
Fluticasone
Flovent (oral inhalation) Flonase (intranasal) Corticosteroids
55
Triamcinolone acetonide
Azmacort | Corticosteroids
56
Ciclesonide
Omnaris | Corticosteroids
57
Prednisone
oral | Corticosteroids
58
Nethylprednisolone
IV or oral | Corticosteroids
59
Corticosteroids contraindications
Drug allergy | Inhaled w/: sputum tests for candida organisms, systemic fungal infection
60
Corticosteroids adverse effects
Inhaled: pharyngeal irritation, Coughing, Dry mouth, Oral fungal infections, *wash mouth after use* Systemic effects: adrenocortical insufficiency, increased susceptibility to infection, fluid & electrolyte disturbances, endocrine effects, insomnia, nervousness, seizures, brittle skin, bone loss, osteoporosis, cushing's syndrome bone growth suppressed in children & adolescents
61
Phosphodiesterase 4 inhibitor indications
Prevent coughing, excess mucus from worsening, decrease frequency of life threatening COPD exacerbations
62
Phosphodiesterase 4 inhibitor adverse effects
``` nausea diarrhea headache insomnia dizziness weight loss psychiatric symptoms ```