Chap 37 (exam 4) Flashcards

1
Q
The nurse is teaching a group of patients about the use of bronchodilators. It is important to remind them that using bronchodilators too frequently may cause which adverse effects? Select all that apply
Blurred vision
Increased heart rate
Decreased heart rate
Nausea
Nervousness
Tremors
A

Increased heart rate
Nausea
Nervousness
Tremors

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2
Q

For patients taking a leukotriene receptor antagonist, the nurse should include which information in the patient teaching?
If a dose is missed, the patient may take a double dose to maintain blood levels
The patient should gargle or rinse the mouth after using the inhaler
The medication should be taken at the first sign of bronchospasm
Improvement should be seen within a week of use

A

Improvement should be seen within a week of use

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3
Q
Which drug acts by blocking leukotrienes, thus reducing inflammation in the lungs?
Cromolyn (Intal)
Montelukast (Singulair)
Theophylline (Elixophyllin)
Albuterol (Proventil)
A

Montelukast (Singulair)

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4
Q
A patient is experiencing status asthmaticus. The nurse will prepare to administer which drug first?
Epinephrine
Methylprednisolone (Solu-Medrol)
Cromolyn (Intal)
Montelukast (Singulair)
A

Epinephrine

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5
Q
When a patient is taking parenteral xanthine derivatives such as aminophylline, the nurse should monitor for which adverse effect?
Decreased respirations
Hypotension
Tachycardia
Hypoglycemia
A

Tachycardia

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6
Q
A patient who has asthma may be prescribed which type of inhaled drug for its antiinflammatory effects?
Corticosteroid
Anticholinergic
Xanthine derivative
Beta adrenergic
A

Corticosteroid

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7
Q
A patient is to receive a new prescription for an ipratropium (Atrovent) inhaler. The nurse will assess for which potential contraindications? Select all that apply
Allergy to soy lecithin
Allergy to peanuts
Allergy to iodine products
Hypertension
Seizure disorders
A

Allergy to soy lecithin

Allergy to peanuts

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8
Q

Tom, a 70 year old retiree who smoked for 40 years, has been diagnosed with chronic obstructive pulmonary disease (COPD); the treatment regimen prescribed includes theophylline (Theo-Dur). After a few weeks, Tom tells the nurse that he is experiencing nausea and “bad heartburn at night.” The laboratory studies show the level of theophylline in his blood to be 30 mcg/mL. What might be wrong with Tom, and how can it be corrected?

A

Tom is exhibiting some side effects of theophylline therapy, and the level in his blood is too high (the common therapeutic range for theophylline is a blood level of 10-20 mcg/dL). It is likely that the dosage will be decreased.

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9
Q

Sylvia has come to the clinic today complaining of nausea, palpitations and anxiety. She says that her heart fee’s :as if it’s going to fly out of my chest.” Physical examination confirms an increased heart rate. Sylvia’s records indicate that she as asthma for which she uses an albuterol inhaler. When asked about the inhaler, she states that she uses it “when ever I feel short of breath.” What is causing Sylvia’s complaints?

A

Sylvia is exhibiting dose-related adverse effects of the albuterol. If Sylvia is now using the albuterol more frequently as a rescue inhaler, the health care provider will need to review and adjust her medication regimen

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10
Q

Mrs. V., a 65-year-old office manager, has arthritis, glaucoma, and emphysema. The health care provider is planning treatment for her emphysema.
What 3 types of drugs might be considered for treatment of COPD?
What factor must the provider keep in mind when determining the best drug for Mrs. V.?

A

Anticholinergics, corticosteroids, beta agonists

Of concern is Mrs. V’s glaucoma. Anticholinergics are to be used cautiously in patients with acute narrow angle glaucoma

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11
Q

Several months ago, the physician prescribed an orally administered corticosteroid for Mr. Z., who has chronic bronchial asthma.
What are the disadvantages of administering the corticosteroids orally? Is there an alternative route?
Today the physician adds beclomethasone dipropoinate (Beclovent) to Mr. Z’s drug regimen and also reduces the dosage of the oral corticosteroid. Why was the oral corticosteroid not discontinued.

A

The disadvantage of administering the corticosteroids orally is that they can then lead to systemic effects, such as increased susceptibility to infection, fluid and electrolyte disturbances, endocrine effects, dermatologic effects, and nervous system effects. They can interact with other systemically administered drugs. The advantage of administering corticosteroids by inhalation is that they are delivered directly to the site of action- the lungs. This generally limits, but does not completely prevent, systemic effects.
The use of an inhaled corticosteroid frequently allows for a reduction in the daily dose of the systemic corticosteroid. This reduction should be gradual to prevent Addisonian crisis due to suppression of the adrenal gland.

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12
Q

Alice has been treated for asthma for several months and has the following inhalers: albuterol (Proventil) and fluticasone (Flovent). Which one should she choose if she experiences an asthma attack? Explain your answer

A

The albuterol is a beta agonist that can be used to treat acute bronchospasms. The fluticasone is a corticosteroid and is not effective for acute bronchospasm. Fluticasone us useful for long-term management of asthma and works to reduce inflammation

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13
Q

Justin calls the nurse at the office because he experiences “palpitations and a racing heart” every morning after breakfast. He is taking theophylline (Theo-Dur) as part of his treatment for asthma. Upon questioning, he states that he has been drinking an extra cup of coffee in the morning “to get going” because his coughing has kept him from sleeping well. What could be his problem?

A

He needs to be reminded to avoid foods and beverages that contain caffeine (e.g., chocolate, coffee, cola, cocoa, tea) because their consumption can exacerbate CNS stimulation

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14
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
How does this medication differ from corticosteroids that are used to reduce inflammation?

A

Montelukast, a leukotriene receptor antagonist, works to reduce the inflammatory response in the lungs but does not have the adverse effects that corticosteroids have

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15
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
Jennie says, “I hope this medicine works better than the other one I took when I has an asthma attack.” How will you reply?

A

Leukotriene receptor antagonists are primarily used for prophylaxis and chronic management of asthma and are not appropriate for treatment of acute asthma attacks; however, they should decrease the frequency of the attacks

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16
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
Jennie takes ibuprofen (Advil) on occasion for arthritic pain. How do you advise Jennie regarding taking over the counter drugs with montelukast?

A

You should tell Jennie that she needs to check with her health care provider before taking any over the counter medications

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17
Q

Jennie has been treated for adult-onset asthma for 3 years. She has been doing fairly well with her inhalers, but today she receives a prescription for montelukast (Singulair), one 10 mg tablet daily.
After 3 months, Jennie stops taking the montelukast. She says, “my symptoms are better, and I don’t want to take medicine unless I need it.” Is this appropriate?

A

These drugs should be taken every night on a continuous schedule, even if symptoms improve

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18
Q

A patient who has a history of asthma is experiencing an acute episode of shortness of breath and needs to take a medication for immediate relief. The nurse will choose which medication that is appropriate for this situation?
A beta agonist, such as albuterol
A leukotriene receptor antagonist, such as montelukast
A corticosteroid, such as fluticasone
An anticholinergic, such as ipratropium

A

A beta agonist, such as albuterol

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19
Q

After a nebulizer treatment with the beta agonist albuterol, the patient complains of feeling a little “shaky”, with slight tremors of the hands. The patient’s heart rate is 98 beats/min, increased from the pretreatment rate of 88 beats/min. The nurse knows that this reaction is an:
Expected adverse effect of the medication
Allergic reaction to the medication
Indication that he has received an overdose of the medication
Idiosyncratic reaction to the medication

A

Expected adverse effect of the medication

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20
Q
A patient has been receiving an aminophylline (xanthine derivative) infusion for 24 hours. The nurse will assess for which adverse effect when assessing the patient during the infusion?
CNS depression
Sinus tachycardia
Increased appetite
Temporary urinary retention
A

Sinus tachycardia

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21
Q
During a teaching session for a patient who will be receiving a new prescription for the LTRA montelukast (Singulair), the nurse will tell the patient that the drug has which therapeutic effect?
Improves the respiratory drive
Loosens and removes thickened secretions
Reduces inflammation in the airway
Stimulates immediate a bronchdilation
A

Reduces inflammation in the airway

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22
Q

After the patient takes a dose of an inhaled corticosteroid, such as fluticasone (Flovent), what is the most important action the patient needs to do next?
Hold the breath for 60 seconds
Rinse out the mouth with water
Follow the corticosteroid with a bronchodilator inhaler, if ordered
Repeat the dose in 15 minutes if the patient feels short of breath

A

Rinse out the mouth with water

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23
Q

The nurse is teaching a patient about the inhaler Advair (salmeterol/ fluticasone). Which statements by the patient indicate a correct understanding of this medication? Select all that apply:
“I will rinse my mouth with water after each dose”
“I need to use this inhaler whenever I feel short of breath, but not less than 4 hours between doses”
“This medication is taken twice a day, every 12 hours”
“I can take this inhaler if I get short of breath while exercising”
“I will call my doctor if I notice white patches inside my mouth”

A

“I will rinse my mouth with water after each dose”
“This medication is taken twice a day, every 12 hours”
“I will call my doctor if I notice white patches inside my mouth”

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24
Q

what are the classes of bronchodilators

A

Beta adrenergic adonists
anticholinergic
xanthine derivatives

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25
Q

albuterol

A

Ventolin, Proventil
SABA
beta2 specific bronchodilating beta agonist
Dose-related effects (beta1 stimulated): nausea, increased anxiety, palpitations, tremors, increased heart rate

26
Q

levalbuterol

A

Xopenox
SABA
For pts w/ tachycardia

27
Q

Formoterol

A

Foradil, Perforomist

LABA

28
Q

Salmetrol

A

Serevant
LABA
Never for acute treatment
Used w/ inhaled corticosteroid twice daily
Adverse effects: immediate hypersensitivity reactions, headache, HTN, neuromuscular & skeletal pain

29
Q

Beta adrenergic agonist indications

A

prevention or relief of bronchospasm related to bronchial asthma, bronchitis, other pulmonary diseases

30
Q

Beta adrenergic agonist contraindications

A

Drug allergy
uncontrolled HTN or cardiac dysrhythmias
high risk of stroke

31
Q

Beta adrenergic agonist adverse effects

A

alpha/ beta agonists combos produce most: insomnia, restlessness, anorexia, cardiac stimulation, hyperglycemia, tremor, vascular headache
beta2 drugs: HTN, hypotension, vascular headaches, tremor

32
Q

Beta adrenergic agonist interaction

A

Nonselective beta blockers w/ beta agonist bronchodilator: beta agonist bronchodilation diminishes
Beta agonists w/ MAOIs: enhanced risk of HTN
Pts w/ diabetes need lower hypoglycemic drugs due to increased blood glucose may occur

33
Q

ipratropium

A

Atrovent

Anticholinergic bronchodilator

34
Q

tiotropium

A

Spiriva

Anticholinergic bronchodilator

35
Q

Anticholinergic bronchodilator contraindications

A

drug allergy
Allergy to atropine or soy lecithin
Allergy to peanuts, peanut oils, soybeans, other legumes

36
Q

Anticholinergic bronchodilator adverse effects

A
dry mouth or throat
nasal congestion
heart palpitations
GI distress
Urinary retention
Increased intraocular pressure
headache
coughing 
anxiety
37
Q

Xanthine derivatives

A

Theophylline (metabolized to caffeine in body)
Caffeine
Aminophylline (metabolized to theophylline in body)

38
Q

Xanthine derivatives mechanism of action

A

Inhibit phosphodiesterase, which increases cAMP levels, causes bronchodilation

39
Q

Xanthine derivatives indications

A

dilate airways of pts w/ asthma, chronic bronchitis, emphysema
Mild to moderate causes of acute asthma
Adjunct drug managing COPD

40
Q

Xanthine derivatives contraindications

A
Drug allergy
uncontrolled cardiac dysrhythmias
seizure disorders
hyperthyroidism
peptic ulcers
41
Q

Xanthine derivatives adverse effects

A
nausea
vomiting
anorexia
gastroesophageal refluc
sinus tachycardia
palpitations
extrasystole
ventricular dysrhythmias
42
Q

Theophylline

A

metabolized to caffeine in body

therapeutic blood level 10-20 mcg/mL

43
Q

Leukotriene receptor antagonists

A

LTRAs

44
Q

Montelukast

A

Singulair
LTRA
Bind to D4 leukotriene receptor subtype in respiratory tract tissues & organs
Only oral

45
Q

Zafirlukast

A

Accolate
LTRA
Bind to D4 leukotriene receptor subtype in respiratory tract tissues & organs
Adverse effects: headache, nausea, diarrhea

46
Q

Zileuton

A
Zyflo
LTRA
Indirect mechanism
Inhibits enzyme 5-lipoxygenase
Adverse effects: headache, nausea, dizziness, incomnia
47
Q

LTRA indications

A

prophylaxis & long-term treatment & prevention of asthma in adults & children 12 and up
Not for acute attacks
Improvement in about 1 week

48
Q

LTRA contraindications

A

drug allergy

allergy to povidone, lactose, titanium dioxide, cellulose derivatives,

49
Q

Corticosteroids

Mechanism of action

A

Glucocorticoids

dual effect of reducing inflammation & enhancing activity of beta agonists

50
Q

Beclomthasone diproprionate

A

Beclovent

Corticosteroids

51
Q

Budesonide

A

Pulmicart Turbuhaler

Corticosteroids

52
Q

Dexamethasone sodium phosphate

A

Decardon Phosphate Respihaler

Corticosteroids

53
Q

Flunisolide

A

AeroBid

Corticosteroids

54
Q

Fluticasone

A

Flovent (oral inhalation)
Flonase (intranasal)
Corticosteroids

55
Q

Triamcinolone acetonide

A

Azmacort

Corticosteroids

56
Q

Ciclesonide

A

Omnaris

Corticosteroids

57
Q

Prednisone

A

oral

Corticosteroids

58
Q

Nethylprednisolone

A

IV or oral

Corticosteroids

59
Q

Corticosteroids contraindications

A

Drug allergy

Inhaled w/: sputum tests for candida organisms, systemic fungal infection

60
Q

Corticosteroids adverse effects

A

Inhaled: pharyngeal irritation, Coughing, Dry mouth, Oral fungal infections, wash mouth after use
Systemic effects: adrenocortical insufficiency, increased susceptibility to infection, fluid & electrolyte disturbances, endocrine effects, insomnia, nervousness, seizures, brittle skin, bone loss, osteoporosis, cushing’s syndrome
bone growth suppressed in children & adolescents

61
Q

Phosphodiesterase 4 inhibitor indications

A

Prevent coughing, excess mucus from worsening, decrease frequency of life threatening COPD exacerbations

62
Q

Phosphodiesterase 4 inhibitor adverse effects

A
nausea
diarrhea
headache
insomnia
dizziness
weight loss
psychiatric symptoms