Chap 20 (exam 2) Flashcards
Atropine
Antidote for overdose of a cholinergic drug
Indirect-acting cholinergic drugs
Cholinergic drugs that act by making more acetylecholine (ACh) available at the receptor site, thus allowing ACh to bind to and stimulate the receptor
Direct-acting cholinergic drugs
Cholinergic drugs that bind to cholinergic receptors and activate them
Muscarinic
Receptors located post synaptically in the effector organs (smooth muscle, cardiac muscle, glands) supplied by the parasympathetic fibers
Nicotinic
Receptors located in the ganglia of the parasympathetic nervous system (PSNS) and the sympathetic nervous system (SNS)
Rest and Digest
A description of the action of the PSNS
Acetylcholine
The neurotransmitter responsible for the transmission of the nerve impulses to the effector cells in the PSNS
Cholinesterase
The enzyme responsible for breaking down ACh
The desired effects of cholinergic drugs come from stimulation of which receptors? Cholinergic Nicotinic Muscarinic Ganglionic
Muscarinic
The undesirable effects of cholinergic drugs come from stimulation of which receptors? Cholinergic Nicotinic Muscarinic Ganglionic
Nicotinic
The patient mentions bethanechol (Urecholine) when asked about his medication history. The nurse recognizes that this drug is used for the treatment of which condition? Diarrhea Urinary retention Urinary incontinence Bladder spasm
Urinary retention
When caring for a patient with a diagnosis of myasthnia gravis, the nurse can expect to see which drug ordered for the symptomatic treatment of this disease? Bethanechol (Urecholine) Tacrine (Cognex) Donepezil (Aricept) Pyridostigmine (Mestinon)
Pyridostigmine (Mestinon)
A 62 year old woman has started taking donepezil (Aricept) for early stage Alzheimer’s disease. Her daughter expresses relief that “there is finally a pill to cure Alzheimer’s disease.” What is the nurse’s best response?
“She can expect reversal of symptoms within a few days”
“The dosage will need to be increased if no improvement is noted”
“This drug may help to improve symptoms, but it is not intended as a cure”
“Yes, it has been a great help for many patients”
“This drug may help to improve symptoms, but it is not intended as a cure”
A patient has received an inadvertent overdose of a cholinergic drug. The nurse will monitor for which early signs of a cholinergic crisis? Select all that apply: Dry mouth Salivation Flushing of the skin Abdominal cramps Constipation Dyspnea
Salivation
Flushing of the skin
Abdominal cramps
Dyspnea
The nurse will prepare to give which drug to a patient who is experiencing a cholinergic crisis? Atropine Tacrine (Cognex) Donepezil (Aricept) Physostigmine (Antilirium)
Atropine
