CH27 Antimicrobial Therapy Flashcards

1
Q

antibiotics that taget cell wall synthesis hint: PCBV

A

-peniccillin
-cephalosporin
-bacitracin
-vancomycin

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2
Q

antibiotics that target protein synthesis hint: CTAML

A

-chloramphenicol
-tetracyclines
-aminoglycosides
-macrolides
-lincosamides

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3
Q

antibiotics that target cell membrane hint: PDAI

A

-polymyxin
-daptomycin
-amphotericin
-imidazoles (vs fungi)

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4
Q

antibiotics that target nucleic acid function Hint: NNQR

A

-nitroimidazoles
-nitrofurans
-quinolones
-rifampin

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5
Q

antibiotics that target intermediary metabolism hint: ST

A

-sulfonamides
-trimethoprim

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6
Q

if you have resistance to vancomycin what should you use?

A

teixobectin

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7
Q

what are the two penicillin strains capable of gram-negative bacterial treatment

A

-methicillin
-carbencillin (pseudomonas infections)

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8
Q

synthetic protein synthesis antibacterial that only hits gram-positive bacteria is called what? and why does it only hit gram-positive bacteria?

A

F. Linezolid
- only gram positive because of eflux pumps

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9
Q

when the agar plate has mucoid colonies what does that tell you?

A

there is a lot of capsule production

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10
Q

what does ESKAPE stand for

A

ESKAPE is an acronym for a group of bacteria that are highly dangerous and deadly
- ESKAPE stands for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species

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11
Q

what antiviral drug inhibits the M2 protein and fights influenza virus

A

amantadine (prevents viral uncoating)

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12
Q

what antiviral drug is used to fight H1N1

A

tamiflu (neuraminidase inhibitor)

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13
Q

what antiviral drug is a guanosine analog

A

acyclovir

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14
Q

what antiviral drug is absorbed 80% and fights herpes

A

famciclovir

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15
Q

what is a prodrug

A

a biologically inactive compound which can be metabolized in the body to produce a drug.

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16
Q

what antiviral drug is used to fight HIV

A

AZT (inhibits reverse transcriptase)

17
Q

what is an antifungal that turns you purple

A

gentian violet
- used to treat fungus infections inside the mouth (thrush) and of the skin.

18
Q

if there is no oh group on the nucleotide (deoxy) then what happens to the nucleotide

A

is the 3’ OH group is absent then there wont be addition of new nucleotides in the polynucleotide chain (the rxn would stop)

19
Q

what are dNTPs (deoxynucleotides)

A

The substrates for DNA polymerizing enzymes

20
Q

video for sangers DNA sequencing method

A

https://www.youtube.com/watch?v=KTstRrDTmWI

21
Q

what does deep-branching mean

A

bacteria that appear to have diverged the earliest from ancestral archaea and eukaryotes