Ch12: Neoplasia Part II

Question 1

What are the 3 main categories of neoplasms?

Answer 1

1. Benign
2. Low malignant potential
3. Malignant

Question 2

Classification criteria for benign vs. malignant? (5)

Answer 2

Growth Characteristics
Rate of Proliferation and Cell Death
Differentiation
Invasion
Metastasis

Question 3

Differentiate benign and malignant based on growth pattern?

Answer 3

Benign: Expansive
Malignant: Infiltrative

Question 4

Differentiate benign and malignant based on rate of growth

Answer 4

Benign: Slow
Malignant: fast

Question 5

Differentiate benign and malignant based on differentiation?

Answer 5

Benign: Very well differentiated
Malignant: Poorly differentiated to well

Question 6

Differentiate benign and malignant based on metastasis?

Answer 6

Benign: none
malignant: typical

Question 7

What are the two types of benign neoplasms based on histogenesis?

Answer 7

Benign epithelial neoplasm

Benign mesenchymal neoplasm

Question 8

What are the four types of benign neoplasms based on histogenesis and cellular features?

Answer 8

Malignant epithelial neoplasm: Carcinoma
Malignant mesenchymal neoplasm: Sarcoma
Malignant neoplasm of lymphoid cells: Lymphoma
Malignant neoplasm of blood elements: Leukemia

Question 9

Where do leukemias arise?

What will you see?

Answer 9

Within the marrow

see malignant cells within the blood

Question 10

Where do lymphomas arise?

Answer 10

Lymph node

see malignant cells in tissues

Question 11

A squamous cell carcinoma appears what color?

What other features? (4)

Answer 11

Eosinophilic: Pink

Keratin: Keratin pearl
Dark nucleus
IC clear spaces
IC bridges

Question 12

Adenocarcinoma appear how?

Answer 12

1. Acentral nuclei
2. no desmosomes
3. Forms glands with lumens
4. Keratin