Ch. 8 - Psoriasiform and spongiotic dermatitis Flashcards

1
Q

Psoriasis

A

Alternating neutrophils and parakeratosis in stratum corneum (sandwich sign), neutrophilic spongiform pustules, tortuous blood vessels in dermal papillae.

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2
Q

What lesions can present with collections of neutrophils within the stratum corneum?

A

Psoriasis

Tinea

Impetigo

Candida

Seborrheic dermatitis

Syphilis

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3
Q

Plaque psoriasis

A

Sandwich sign, neutrophilic spongiform pustules, regular bulbous acanthosis and thin superpapillary plates.

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4
Q

Pustular psoriasis

A

Neutrophils in the stratum corneum with subcorneal and spongiform pustules.

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5
Q

Guttate psoriasis

A

Neutrophils on top of parakeratosis. No acanthosis.

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6
Q

ILVEN

A

Alternating orthokeratosis (with granular layer) and parakeratosis (without underlying granular layer)

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7
Q

Mycosis fungoides

A

Epidermal collection of hyperchromatic lymphocytes surrounded by white space. Spongiosis and papillary dermal fibrosis.

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8
Q

Syphilis

A

Vacuolar interface dermatitis with elongated psoriasiform acanthosis. Neutrophils in stratum corneum. Perivascular lymphoplasmacytic infiltrate. Endothelial swelling.

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9
Q

What cutaneous lesions are associated with plasma cells?

A

Kaposi’s sarcoma

Syphilis

Leishmaniasis

Rhinoscleroma

Melanoma

Squamous cell carcinoma

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10
Q

Nutritional-deficiency dermatitis

A

Pallor and ballooning of upper epidermis. Consider glucagonoma, pellagra, acrodermatitis enteropathica.

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11
Q

Granular parakeratosis

A

Compact hyperkeratosis with parakeratosis and preserved granular layer.

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12
Q

Porokeratosis

A

Cornoid lamellae with intervening lichenoid or psoriasiform zones

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13
Q

Acute spongiotic dermatitis

A

Spongiosis, exocytosis of lymphocytes

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14
Q

Seborrheic dermatitis

A

Psoriasiform spongiotic dermatitis with neutrophilic scale/crust at edges of follicular ostium

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15
Q

Subacute spongiotic dermatitis

A

Parakeratosis, acanthosis, spongiosis, and exocytosis of lymphocytes

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16
Q

What are some common causes of spongiotic dermatitis?

A

Allergic contact dermatitis (eczema)

Dyshidrotic dermatitis

Nummular dermatitis

Stasis dermatitis

Pityriasis rosea

Tinea

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17
Q

Chronic dermatitis (lichen simplex chronicus)

A

Compact stratum corneum with irregular acanthosis, papillary dermofibrosis, and focal epidermal necrosis (from excoriation)

18
Q

Pityriasis rosea

A

Subacute spongiotic dermatitis with erythrocyte extravasation and transepidermal elimination of erythrocytes

19
Q

Spongiotic pigmented purpuric eruption (PPE)

A

Spongiosis with purely lymphoid perivascular inflammation and erythrocyte extravasation.

20
Q

Stasis dermatitis

A

Subacute spongiotic dermatitis with cannonball-like angioplasia in the superficial dermis. Hemosiderin?

21
Q

What can cause spongiotic dermatitis with intraepidermal eosinophils?

A

Herpes gestationis

Arthropod bite

Allergic contact dermatitis

Pephigus

Pemphigoid

Incontinentia pigmenti

Erythema toxicum

22
Q

Zoon’s balanitis

A

Spongiosis with flattened, diamond-shaped keratinocytes and dermal plasma cells.

23
Q

Pityriasis rubra pilarris

A

Acanthosis with thick superpapillary plates and parakeratosis adjacent to follicles.

24
Q
A

Plaque psoriasis

25
Q
A

Pustular psoriasis

26
Q
A

Guttate psoriasis

27
Q
A

ILVEN

28
Q
A

Psoriasiform mycosis fungoides

29
Q
A

Syphilis

30
Q
A

Deficiency dermatitis

31
Q
A

Granular parakeratosis

32
Q
A

Porokeratosis

33
Q
A

Pityriasis rosea

34
Q
A

Pigmented purpuric eruption

35
Q
A

Acute spongiform dermatitis

36
Q
A

Subacute spongiotic dermatitis

37
Q
A

Lichen simplex chronicus

38
Q
A

Stasis dermatitis

39
Q
A

Pemphigoid

40
Q
A

Zoon’s balanitis

41
Q
A

Pityriasis rubra pilaris