Ch. 8 - Psoriasiform and spongiotic dermatitis Flashcards
Psoriasis
Alternating neutrophils and parakeratosis in stratum corneum (sandwich sign), neutrophilic spongiform pustules, tortuous blood vessels in dermal papillae.
What lesions can present with collections of neutrophils within the stratum corneum?
Psoriasis
Tinea
Impetigo
Candida
Seborrheic dermatitis
Syphilis
Plaque psoriasis
Sandwich sign, neutrophilic spongiform pustules, regular bulbous acanthosis and thin superpapillary plates.
Pustular psoriasis
Neutrophils in the stratum corneum with subcorneal and spongiform pustules.
Guttate psoriasis
Neutrophils on top of parakeratosis. No acanthosis.
ILVEN
Alternating orthokeratosis (with granular layer) and parakeratosis (without underlying granular layer)
Mycosis fungoides
Epidermal collection of hyperchromatic lymphocytes surrounded by white space. Spongiosis and papillary dermal fibrosis.
Syphilis
Vacuolar interface dermatitis with elongated psoriasiform acanthosis. Neutrophils in stratum corneum. Perivascular lymphoplasmacytic infiltrate. Endothelial swelling.
What cutaneous lesions are associated with plasma cells?
Kaposi’s sarcoma
Syphilis
Leishmaniasis
Rhinoscleroma
Melanoma
Squamous cell carcinoma
Nutritional-deficiency dermatitis
Pallor and ballooning of upper epidermis. Consider glucagonoma, pellagra, acrodermatitis enteropathica.
Granular parakeratosis
Compact hyperkeratosis with parakeratosis and preserved granular layer.
Porokeratosis
Cornoid lamellae with intervening lichenoid or psoriasiform zones
Acute spongiotic dermatitis
Spongiosis, exocytosis of lymphocytes
Seborrheic dermatitis
Psoriasiform spongiotic dermatitis with neutrophilic scale/crust at edges of follicular ostium
Subacute spongiotic dermatitis
Parakeratosis, acanthosis, spongiosis, and exocytosis of lymphocytes
What are some common causes of spongiotic dermatitis?
Allergic contact dermatitis (eczema)
Dyshidrotic dermatitis
Nummular dermatitis
Stasis dermatitis
Pityriasis rosea
Tinea
Chronic dermatitis (lichen simplex chronicus)
Compact stratum corneum with irregular acanthosis, papillary dermofibrosis, and focal epidermal necrosis (from excoriation)
Pityriasis rosea
Subacute spongiotic dermatitis with erythrocyte extravasation and transepidermal elimination of erythrocytes
Spongiotic pigmented purpuric eruption (PPE)
Spongiosis with purely lymphoid perivascular inflammation and erythrocyte extravasation.
Stasis dermatitis
Subacute spongiotic dermatitis with cannonball-like angioplasia in the superficial dermis. Hemosiderin?
What can cause spongiotic dermatitis with intraepidermal eosinophils?
Herpes gestationis
Arthropod bite
Allergic contact dermatitis
Pephigus
Pemphigoid
Incontinentia pigmenti
Erythema toxicum
Zoon’s balanitis
Spongiosis with flattened, diamond-shaped keratinocytes and dermal plasma cells.
Pityriasis rubra pilarris
Acanthosis with thick superpapillary plates and parakeratosis adjacent to follicles.
Plaque psoriasis
