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Derm1 > Ch. 4 - Pilar & sebaceous neoplasms > Flashcards

Ch. 4 - Pilar & sebaceous neoplasms Flashcards

1
Q

Pilomatricoma (calcifying epithelioma of Malherbe)

A

Large ball with internal trabeculae. Basophilic cells keratinizing to form shadow cells. Calcification (or bone fomration!) with giant cell granulomas.

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2
Q

Pilomatrical carcinoma

A

Rare atypical and infiltrative lesions that arises in long-standing pilomatricomas.

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3
Q

Trichoblastoma

A

Blue follicular tumors composed of basaloid cells. No retraction artifact. Stroma resembles normal fibrous sheath with contentric collagen and papillary mesenchymal bodies.

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4
Q

Trichoepithelioma

A

A type of trichoblastoma with finger-like projections and cribriform nodules.

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5
Q

Name 3 syndromes associated with trichoepitheliomas.

A

Multiple trichoepitheliomas (AD-inherited)

Brooke-Spiegler syndrome (+cylindromas)

Rombo syndrome (+milia, hypotrichosis)

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6
Q

Desmoplastic trichoepithelioma

A

Firm doughnut-shaped lesion with central dell and Paisley-tie pattern. Red desmoplastic stroma. Affects young women.

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7
Q

Name 5 lesions that show “Paisley-tie” morphology.

A

Desmoplastic trichoepithelioma

Microcystic adnexal carcinoma

Morpheaform BCC

Eruptive syringomas

Syringomas

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8
Q

Lymphadenoma (adamantinoid trichoblastoma)

A

Tumor islands with 1-2 layers of basaloid cells peripherally and clear/inflammatory cells centrally.

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9
Q

Fibrofolliculoma

A

Fibrous pink orb with radiating epithelial strands. No hair fibers.

*associated with Birt-Hogg-Dube syndrome*

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10
Q

Trichofolliculoma

A

Many small hair follicles emptying into a large follicular infundibulum. Many small hair shafts.

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11
Q

Trichoadenoma

A

Multiple “red doughnuts” in the dermis resembling follicular infundibulum. Often in pairs?

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12
Q

Basaloid follicular hamartoma

A

Resembles infundibulocystic BCC (distinguish clinically). Can be multiple (AD-inherited) with blaschkoid distribution.

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13
Q

Dilated pore of Winer

A

Resembling a dilated follicular infundibulum, with small radiationg epithelial projections.

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14
Q

Pilar sheath acanthoma

A

Similar to dilated pore of Winer, but with thick acanthotic fingers

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15
Q

Trichlemmoma

A

Warty-surfaced lobules of clear cells and peripheral palisading. Outlined by thick glassy eosinophilic basement membranous.

*associated with Cowden’s syndrome*

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16
Q

Desmoplastic trichilemmoma

A

Smooth outline with surrounding glassy basement membrane. Centrally desmoplastic.

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17
Q

Nevus sebaceus of Jadassohn (organoid nevus)

A

Broad and alopecic lesion that becomes papillomatous and hyperkeratotic after puberty.

18
Q

Sebaceous hyperplasia

A

Cluster of mature sebaceous glands around a patulous follicular opening. Nominal basaloid layer at periphery.

19
Q

Sebaceoma

A

Single nodule with varying proportions of basaloid cells (sebacoeous epithelioma) and sebocytes (sebaceous adenoma).

*associated with Muir-Torre syndrome*

20
Q

Sebaceous carcinoma

A

Atypical and infiltrative lesion with foamy cells with scalloped nuclei and buckshot spread.

21
Q
A

Pilomatricoma (low-power)

22
Q
A

Pilomatricoma (high-power)

23
Q
A

Pilomatrical carcinoma

24
Q
A

Trichoblastoma

25
Q
A

Trichoepithelioma

26
Q
A

Desmoplastic trichoepithelioma

27
Q
A

Lymphadenoma

28
Q
A

Fibrofolliculoma

29
Q
A

Trichofolliculoma

30
Q
A

Trichoadenoma

31
Q
A

Basaloid follicular hamartoma

32
Q
A

Dilated pore of Winer

33
Q
A

Pilar sheath acanthoma

34
Q
A

Trichilemmoma

35
Q
A

Desmoplastic trichilemmoma

36
Q
A

Postpubertal nevus sebaceus of Jadassohn

37
Q
A

Prepubertal nevus sebaceus of Jadassohn

38
Q
A

Sebaceous hyperplasia

39
Q
A

Sebaceoma

40
Q
A

Sebaceous carcinoma

Derm1 (30 decks)

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