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Derm1 > Ch. 23 - Vascular tumors > Flashcards

Ch. 23 - Vascular tumors Flashcards

1
Q

Angiokeratoma

A

Hyperkeratotic/acanthotic collection of ectatic thin-walled vessels in the epidermis. “Bloody seborrheic keratosis”

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2
Q

Lmphangioma

A

Similar to angiokeratoma with lymph in vessels, but few erythrocytes. D2-40+

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3
Q

Nevus flammeus

A

Dilated capillary-sized vessels

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4
Q

Angioma serpiginosum

A

Dilated tortuous capillaries in dermal papillae and upper dermis. No alk-phos activity.

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5
Q

Venous lake

A

Irregular, thin-walled ectactic vessel. Blanches and collapses easily.

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6
Q

Glomus tumor

(IHC?)

A

Rows of round dark nuclei with little cytoplasm surrounding delicate vascular spaces.

SMA+ / CD31-

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7
Q

Glomangioma

A

One to two layers of round dark nuclei surrounding thick-walled vessels.

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8
Q

Pyogenic granuloma (lobular capillary hemangioma)

A

Eruptive lobular lesion with packed endothelial cells, ectatic vessels, erosion and crusting. Often impetiginized.

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9
Q

Bacillary angiomatosis

A

Not-very-lobular collection of inflammatory cells and vessels. Neutrophils and organisms present.

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10
Q

Cherry angioma

A

Capillary hemangioma with pink hyalinized vessel walls.

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11
Q

Infantile hemangioma

(IHC?)

A

Initially solidly packed, later ectatic vessels.

GLUT1+

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12
Q

Angiolymphoid hyperplasia with eosinophilia

A

Central thick-walled hobnailed vessels with peripheral smaller vessels. Nodular lymphoid aggregegates with eosinophils.

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13
Q

Kimura’s disease

A

Small vessels with deep lymphoid nodules with eosinophils and peripheral eosinophilia and elevated IgE.

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14
Q

Intravascular papillary endothelial hyperplasia of Masson (IPEH)

A

Recanalizing thrombus within a vascular space with papillary projections with hyalinized cores.

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15
Q

Arteriovenous malformation (arteriovenous hemangioma)

A

Thick- and thin-walled vessels. Thick-walled vessels tend to be central.

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16
Q

Targetoid hemosiderotic hemangioma (hobnail hemangioma)

A

Traumatized hemangioma with peripheral vascular proliferation surrounding existing vessels and adnexae.

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17
Q

Eccrine angiomatous hamartoma

A

Discrete lobules composed of capillaries, mature eccrine glands, and ducts.

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18
Q

Glomeruloid hemangioma

(associations?)

A

Capillary loops within a dilated vascular space, resembling a glomerulus.

(POEMS, Castleman’s disease)

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19
Q

Microvenular hemangioma

(association?)

A

Monomorphous, elongated blood vessels with small lumens surrounding pericytes

(occurs in POEMS syndrome)

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20
Q

Tufted angioam (angioblastoma)

A

“Cannonball” tufts of capillary-sized vessels in the dermis which expand slowly.

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21
Q

Kaposiform hemangioendothelioma

(association?)

A

Large lobules of spindled endothelial cells forming slit-like and staghorn vascular spaces. Deep-seated, can involve bone.

Kasabach-Merritt coagulopathy

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22
Q

Hemangiopericytoma

A

Starghorned vessels surrounded by a proliferation of spindle-cell pericytes. Probably a solitary fibrous tumor?

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23
Q

Spindle cell hemangioma (spindle cell hemangioendothelioma)

A

Solid area of spindle cells with alveolar spaces resembling hemorrhagic lung. Phleboliths.

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24
Q

Epithelioid hemangioendothelioma

A

Dilated vascular channels with solid epithelioid and spindle cell areas. Intracytoplasmic lumens and some atypia.

25
Q

Retiform hemangioendothelioma

A

Arborizing blood vessels reminiscent of rete testis. A low-grade angiosarcoma.

26
Q

Angiosarcoma

(IHC?)

A

Crack-like spaces between collagen lined by hyperchromatic endothelial cells. Atypia.

CD34/31+, Factor VIII+ (unreliable), D2-40+

27
Q

Kaposi’s sarcoma, early-patch-stage

A

Bizarre staghorn ectatic lymphatic-like vessles with plasma cells.

28
Q

Kaposi’s sarcoma, late-patch-stage

A

Pale busy dermis surrounding adnexae with promontory sign (pre-exising structure protruding into lake-like ectatic space)

29
Q

Nodular kaposi’s sarcoma

A

Nodules composed of atypical spindle cells with erythrocytes, eosinophilic globules, and hemosiderin.

30
Q
A

Angiokeratoma

31
Q
A

Lymphangioma

32
Q
A

Nevus flammeus

33
Q
A

Angioma serpiginosum

34
Q
A

Venous lake

35
Q
A

Glomus tumor

36
Q
A

Glomangioma

37
Q
A

Pyogenic granuloma

38
Q
A

Bacillary angiomatosis

39
Q
A

Cherry angioma

40
Q
A

Infantile hemangioma

41
Q
A

Angiolymphoid hyperplasia with eosinophilia

42
Q
A

Kimura’s disease

43
Q
A

Intravascular papillary endothelial hyperplasia

44
Q
A

Arteriovenous malformation

45
Q
A

Targetoid hemosiderotic hemangioma

46
Q
A

Eccrine angiomatous hamartoma

47
Q
A

Glomeruloid hemangioma

48
Q
A

Microvenular hemangioma

49
Q
A

Tufted angioma

50
Q
A

Kaposiform hemangioendothelioma

51
Q
A

Hemangiopericytoma

52
Q
A

Epithelioid hemangioendothelioma

53
Q
A

Spindle-cell hemangioendothelioma

54
Q
A

Retiform hemangioendothelioma

55
Q
A

Angiosarcoma

56
Q
A

Early patch Kaposi’s sarcoma

57
Q
A

Plaque Kaposi’s sarcoma

58
Q
A

Nodular Kaposi’s sarcoma

Derm1 (30 decks)

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