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Derm1 > Ch. 19 - Viral infections, helminths, and arthropods > Flashcards

Ch. 19 - Viral infections, helminths, and arthropods Flashcards

1
Q

Verruca vulgaris

A

Exophytic papillomatous mass with compact eosinophilic hyperkeratosis. Koilocytes may be present.

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2
Q

Myrmecia

A

Deep palmoplantar wart with anthill-like appearance. Associated with HPV-1.

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3
Q

Verruca plana (flat wart)

A

Coarse basket-weave hyperkeratosis with hypergranulosis and “Bird’s eye” cells

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4
Q

Epidermodysplasia verruciformis (EDV)

A

Widespread flat warts with foamy blue cytoplasm

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5
Q

Condyloma acuminatum

A

Benign acanthoma on genital skin with vacuolated keratinocytes (true koilocytes are rare).

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6
Q

Bowenoid papulosis

A

Discrete sessile genital lesion with full-thickness atypia. Associated with HPV-16.

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7
Q

Heck’s disease

A

Focal oral hyperplasia. Hyperkeratosis with “round parakeratosis” and epithelial pallor. Associated with HPV-13 and -32.

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8
Q

Verrucous cyst (cystic papilloma)

A

Cyst with wart-like lining. Resembles myrmecia on feet.

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9
Q

Herpes simplex

A

Ballooning degeneration of keratinocytes with multinucleation and nuclear molding. Herpetic cytopathic effect. Mild leukocytoclastic vasculitis.

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10
Q

Herpes zoster (VZV)

A

Ballooning degeneration of keratinocytes with multinucleation and cytopathic effect. Dramatic leukocytoclastic vasculitis.

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11
Q

Chicken pox (VZV)

A

Ballooning degeneration of keratinocytes with multinucleation and cytopathic effect. Mild leukocytoclastic vasculitis.

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12
Q

Verrucous VZV infection

A

Hyperkeratosis and papillomatosis with follicular herpetic cytopathic effect. Usually in HIV+ patients.

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13
Q

Cytomegalovirus

A

Large endothelial cells with owl’s-eye nuclei.

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14
Q

Smallpox (variola)

A

Epidermal necrosis with reticular degeneration, eosinophilic inclusions (Guarnieri bodies), and nuclear inclusions

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15
Q

Monkey pox

A

Ballooning degeneration of basal keratinocytes with syncytia. Epidermal necrosis and spongiosis. Band-like and perivascular+periadnexal infiltrate.

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16
Q

Molluscum contagiosum

A

Cup-shaped lesion with scalloped border. Contains Henderson-Paterson bodies.

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17
Q

Orf and milker’s nodules

A

Epidermal necrosis with viral inclusion bodies. Long slender acanthosis?

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18
Q

Gianotti-Crosti syndrome

A

Papular acrolocated syndrome with papillary dermal edema, crust, and perivascular lymphoid infiltrate. HPV/HBV.

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19
Q

Hand, foot, and mouth syndrome

A

Oval vesicles with reticular and ballooning degeneration. Coxsackievirus.

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20
Q

Schistosomiasis

(types?)

A

Ova with stippled contents and a mixed, often granulomatous inflammatory response.

  • *Haematobium**: Thin wall, vertical spine
  • *Mansoni**: Thick wall, lateral spine
  • *Japonicum**: Thick wall, no spine
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21
Q

Flatworms

A

Secretory tegument, rows of subtegumental cells. Calcareous bodies (waste), smooth muscle. No gut.

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22
Q

Elephantiasis

A

Filarial roundworms within lymphatic vessels (inflammatory response causes lymphedema)

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23
Q

Onchocercoma / microfilaria

A

Ball of male+female convoluted worms. Thin layer of striated muscle, corrugated cuticle. Large cephalic and caudal spaces.

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24
Q

Dirofilariasis

A

Thick muscular layer interrupted by lateral cords. Internal chitinous ridge.

25
Q

Scabies

A

Mite, ova, or scybala in stratum cornea. Chitin scrolls/pigtails. Subepidermal bulla with eosinophils. Can mimic bullous pemphigoid or langerhans cell histiocytosis.

26
Q

Insect bite

A

Dense wedge-shaped perivascular lymphoid infiltrate with eosinophils and variable vascular damage / atypical lymphocytes.

27
Q

Insect sting

A

Highly variable. Often urticarial reaction followed by late stage fibrin/eosinophils/neutrophils.

28
Q

Tick, tick bite

A

Wedge-shaped inflammation and necrosis. Look for pigmented mouthparts, blood-filled gut.

29
Q

Myiasis

A

Fly larva with thick corrugated chitinous wall, pigmented setae, striated muscle, and gut.

30
Q

Tungiasis

A

Organism with red hollow tubules, gut, striated muscle in acral skin.

31
Q
A

Verruca vulgaris

32
Q
33
Q
A

Verruca plana

34
Q
A

Condyloma acuminatum

35
Q
A

Bowenoid papulosis

36
Q
A

Verrucous cyst

37
Q
A

Herpes simplex

38
Q
A

Herpes zoster (shingles)

39
Q
A

Varicella (chicken pox)

40
Q
A

Verrucous zoster

41
Q
A

Cytomegalovirus

42
Q
A

Smallpox (variola)

43
Q
44
Q
A

Molluscum contagiosum

45
Q
A

Orf nodule

46
Q
A

Gianotti-Crosti syndrome

47
Q
A

Hand, foot, and mouth disease

48
Q
A

Cutaneous schistosomiasis

49
Q
A

Sparganum proliferum

50
Q
A

Elephantiasis

51
Q
A

Onchocercoma

52
Q
A

Onchocerca microfilaria

53
Q
A

Subcutaneous dirofilariasis

54
Q
A

Scabies mite

55
Q
A

Insect bite

56
Q
57
Q
58
Q

Derm1 (30 decks)

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